Pancreatitis with Electrocardiographic Changes Mimicking Acute Myocardial Infarction

A 64-year-old woman with mild acute pancreatitis presented with epigastric pain, nausea and vomiting while undergoing hemodialysis for chronic renal insufficiency. Serial electrocardiograms revealed new onset ST segment elevations in leads V2 to V4 mimicking an anterior myocardial infarction, follow...

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Main Authors: Paul Khairy, Pierre Marsolais
Format: Article
Language:English
Published: Wiley 2001-01-01
Series:Canadian Journal of Gastroenterology
Online Access:http://dx.doi.org/10.1155/2001/604386
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author Paul Khairy
Pierre Marsolais
author_facet Paul Khairy
Pierre Marsolais
author_sort Paul Khairy
collection DOAJ
description A 64-year-old woman with mild acute pancreatitis presented with epigastric pain, nausea and vomiting while undergoing hemodialysis for chronic renal insufficiency. Serial electrocardiograms revealed new onset ST segment elevations in leads V2 to V4 mimicking an anterior myocardial infarction, followed by diffusely inverted deep T waves. No cardiac pathology was demonstrated by echocardiography or coronary angiography. A review of the literature and possible pathophysiological mechanisms of electrocardiographic changes in acute pancreatitis, such as metabolic abnormalities, hemodynamic instability, vasopressors, pericarditis, myocarditis, a cardiobiliary reflex, exacerbation of underlying cardiac pathology, coagulopathy and coronary vasospasm, are discussed.
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spelling doaj-art-4667f73282ea456fa4a8ffff9a0d3c852025-02-03T01:00:52ZengWileyCanadian Journal of Gastroenterology0835-79002001-01-0115852252610.1155/2001/604386Pancreatitis with Electrocardiographic Changes Mimicking Acute Myocardial InfarctionPaul Khairy0Pierre Marsolais1Department of Medicine and Intensive Care, Hôpital du Sacré-Coeur de Montréal, Université de Montréal, Montréal, Québec, CanadaDepartment of Medicine and Intensive Care, Hôpital du Sacré-Coeur de Montréal, Université de Montréal, Montréal, Québec, CanadaA 64-year-old woman with mild acute pancreatitis presented with epigastric pain, nausea and vomiting while undergoing hemodialysis for chronic renal insufficiency. Serial electrocardiograms revealed new onset ST segment elevations in leads V2 to V4 mimicking an anterior myocardial infarction, followed by diffusely inverted deep T waves. No cardiac pathology was demonstrated by echocardiography or coronary angiography. A review of the literature and possible pathophysiological mechanisms of electrocardiographic changes in acute pancreatitis, such as metabolic abnormalities, hemodynamic instability, vasopressors, pericarditis, myocarditis, a cardiobiliary reflex, exacerbation of underlying cardiac pathology, coagulopathy and coronary vasospasm, are discussed.http://dx.doi.org/10.1155/2001/604386
spellingShingle Paul Khairy
Pierre Marsolais
Pancreatitis with Electrocardiographic Changes Mimicking Acute Myocardial Infarction
Canadian Journal of Gastroenterology
title Pancreatitis with Electrocardiographic Changes Mimicking Acute Myocardial Infarction
title_full Pancreatitis with Electrocardiographic Changes Mimicking Acute Myocardial Infarction
title_fullStr Pancreatitis with Electrocardiographic Changes Mimicking Acute Myocardial Infarction
title_full_unstemmed Pancreatitis with Electrocardiographic Changes Mimicking Acute Myocardial Infarction
title_short Pancreatitis with Electrocardiographic Changes Mimicking Acute Myocardial Infarction
title_sort pancreatitis with electrocardiographic changes mimicking acute myocardial infarction
url http://dx.doi.org/10.1155/2001/604386
work_keys_str_mv AT paulkhairy pancreatitiswithelectrocardiographicchangesmimickingacutemyocardialinfarction
AT pierremarsolais pancreatitiswithelectrocardiographicchangesmimickingacutemyocardialinfarction