Prevalence of Multidrug-Resistant Escherichia coli Isolated from Drinking Water Sources
The control of infectious diseases is badly endangered by the rise in the number of microorganisms that are resistant to antimicrobial agents. This is because infections caused by resistant microorganisms often fail to respond to conventional treatment, resulting in prolonged illness and greater ris...
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | International Journal of Microbiology |
| Online Access: | http://dx.doi.org/10.1155/2018/7204013 |
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| author | Stephen T. Odonkor Kennedy K. Addo |
| author_facet | Stephen T. Odonkor Kennedy K. Addo |
| author_sort | Stephen T. Odonkor |
| collection | DOAJ |
| description | The control of infectious diseases is badly endangered by the rise in the number of microorganisms that are resistant to antimicrobial agents. This is because infections caused by resistant microorganisms often fail to respond to conventional treatment, resulting in prolonged illness and greater risk of death. Antimicrobial-resistant bacteria are also present in various water sources. This study therefore sought to document the microbiological quality and antibiograms of bacterial isolates (E. coli strains) from six different water sources in order to determine their safety for human consumption and to provide updated antibiotic data for pragmatic treatment of patients. Bacteria isolation and identification was done using API and conventional methods. Antibiotic susceptibility testing was conducted using the Kirby–Bauer method. Results obtained indicated that all the water sources tested were of poor quality. Bacteria isolated included E. coli, Enterobacter spp., Klebsiella spp., Salmonella typhi, Streptococcus spp., Proteus vulgaris, Vibrio cholera, Shigella spp., Pseudomonas aeruginosa, and Enterococcus faecalis. The prevalence of multidrug-resistant E. coli was 49.48%. E. coli isolates showed high resistance patterns to the tested antibiotics. They were most resistant to penicillin (32.99%), cefuroxime (28.87%), erythromycin (23.71%), and tetracycline (21.45%). In contrast, they were susceptible to nitrofurantoin (93.8%), cefotaxime and amikacin (91.75%), gentamicin (90.7%), nalidixic acid (89.65%), ciprofloxacin (74.2%), chloramphenicol (69.07%), pipemidic acid (65.97%), and cefuroxime (52.58%). Sixty-three percent (63%) of the multidrug-resistant E. coli strains recorded a multiple antibiotic resistance (MAR) index value >0.2. The susceptible antibiotics, especially the nitrofurantoin, are hence recommended in the practical treatment of waterborne bacterial diseases. |
| format | Article |
| id | doaj-art-465bb07880da4161b739d6365fc73ba8 |
| institution | Kabale University |
| issn | 1687-918X 1687-9198 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Microbiology |
| spelling | doaj-art-465bb07880da4161b739d6365fc73ba82025-02-03T01:31:18ZengWileyInternational Journal of Microbiology1687-918X1687-91982018-01-01201810.1155/2018/72040137204013Prevalence of Multidrug-Resistant Escherichia coli Isolated from Drinking Water SourcesStephen T. Odonkor0Kennedy K. Addo1Greenhill College, Ghana Institute of Management and Public Administration, Accra, GhanaDepartment of Bacteriology, Noguchi Memorial Institute for Medical Research, University of Ghana, Accra, GhanaThe control of infectious diseases is badly endangered by the rise in the number of microorganisms that are resistant to antimicrobial agents. This is because infections caused by resistant microorganisms often fail to respond to conventional treatment, resulting in prolonged illness and greater risk of death. Antimicrobial-resistant bacteria are also present in various water sources. This study therefore sought to document the microbiological quality and antibiograms of bacterial isolates (E. coli strains) from six different water sources in order to determine their safety for human consumption and to provide updated antibiotic data for pragmatic treatment of patients. Bacteria isolation and identification was done using API and conventional methods. Antibiotic susceptibility testing was conducted using the Kirby–Bauer method. Results obtained indicated that all the water sources tested were of poor quality. Bacteria isolated included E. coli, Enterobacter spp., Klebsiella spp., Salmonella typhi, Streptococcus spp., Proteus vulgaris, Vibrio cholera, Shigella spp., Pseudomonas aeruginosa, and Enterococcus faecalis. The prevalence of multidrug-resistant E. coli was 49.48%. E. coli isolates showed high resistance patterns to the tested antibiotics. They were most resistant to penicillin (32.99%), cefuroxime (28.87%), erythromycin (23.71%), and tetracycline (21.45%). In contrast, they were susceptible to nitrofurantoin (93.8%), cefotaxime and amikacin (91.75%), gentamicin (90.7%), nalidixic acid (89.65%), ciprofloxacin (74.2%), chloramphenicol (69.07%), pipemidic acid (65.97%), and cefuroxime (52.58%). Sixty-three percent (63%) of the multidrug-resistant E. coli strains recorded a multiple antibiotic resistance (MAR) index value >0.2. The susceptible antibiotics, especially the nitrofurantoin, are hence recommended in the practical treatment of waterborne bacterial diseases.http://dx.doi.org/10.1155/2018/7204013 |
| spellingShingle | Stephen T. Odonkor Kennedy K. Addo Prevalence of Multidrug-Resistant Escherichia coli Isolated from Drinking Water Sources International Journal of Microbiology |
| title | Prevalence of Multidrug-Resistant Escherichia coli Isolated from Drinking Water Sources |
| title_full | Prevalence of Multidrug-Resistant Escherichia coli Isolated from Drinking Water Sources |
| title_fullStr | Prevalence of Multidrug-Resistant Escherichia coli Isolated from Drinking Water Sources |
| title_full_unstemmed | Prevalence of Multidrug-Resistant Escherichia coli Isolated from Drinking Water Sources |
| title_short | Prevalence of Multidrug-Resistant Escherichia coli Isolated from Drinking Water Sources |
| title_sort | prevalence of multidrug resistant escherichia coli isolated from drinking water sources |
| url | http://dx.doi.org/10.1155/2018/7204013 |
| work_keys_str_mv | AT stephentodonkor prevalenceofmultidrugresistantescherichiacoliisolatedfromdrinkingwatersources AT kennedykaddo prevalenceofmultidrugresistantescherichiacoliisolatedfromdrinkingwatersources |