Plasma Concentrations of Benzylpenicillin and Cloxacillin in Infective Endocarditis—With Special Reference to Delayed Hypersensitivity Reactions

Plasma Concentrations of Benzylpenicillin and Cloxacillin in Infective Endocarditis—With Special Reference to Delayed Hypersensitivity Reactions

Background: Current antibiotic regimens for infective endocarditis (IE) are effective but pose a high risk of delayed hypersensitivity reactions (DHR). Dose adjustments guided by therapeutic drug monitoring (TDM) could mitigate these risks while maintaining treatment efficacy. This study aimed to in...

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Bibliographic Details
Main Authors: Malin Hägglund, Ulrika Snygg-Martin, Lars Olaison, Michael Stofkoper, Bert Ove Larsson, Magnus Brink
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Antibiotics
Subjects:
therapeutic drug
monitoring
infective endocarditis
beta-lactams
delayed hypersensitivity reaction
beta-lactam fever
Online Access:https://www.mdpi.com/2079-6382/14/1/56
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