Ulcerative Colitis Activity Presenting as Fever of Unknown Origin, in a Patient with Longstanding Disease under Continuous Treatment with Mesalazine
Background. The presence of ulcerative colitis (UC) with no bowel symptoms, as fever of unknown origin (FUO), is uncommon. Objective. To describe the case of an 80-year-old woman who presented with fever, with a history of UC under treatment with mesalazine. Case Presentation. She was admitted due t...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2016/4396256 |
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| author | Panagiota Voukelatou Elissavet Sfendouraki Theodoros Karianos Sofia Saranti Dimitrios Tsitsimelis Ioannis Vrettos Andreas Kalliakmanis |
| author_facet | Panagiota Voukelatou Elissavet Sfendouraki Theodoros Karianos Sofia Saranti Dimitrios Tsitsimelis Ioannis Vrettos Andreas Kalliakmanis |
| author_sort | Panagiota Voukelatou |
| collection | DOAJ |
| description | Background. The presence of ulcerative colitis (UC) with no bowel symptoms, as fever of unknown origin (FUO), is uncommon. Objective. To describe the case of an 80-year-old woman who presented with fever, with a history of UC under treatment with mesalazine. Case Presentation. She was admitted due to fever lasting for 12 days with no associated symptoms. Seven years earlier, she was diagnosed with UC. After an extended workup for FUO that failed to reach the diagnosis, she underwent a gallium-67 scintigraphy. This revealed a persistent diffuse concentration of gallium-67 in the ascending colon at 24-hour imaging that remained stable at 48- and 72-hour imaging without any topographic change after the use of laxatives. Considering the results and in the absence of another diagnosis, the patient was treated with 30 mg prednisone daily and mesalazine, as treatment of active UC. Subsequently, the patient’s condition improved markedly and the fever retreated. One month later, she was reevaluated with a gallium-67 scintigraphy with total absence of gallium-67 concentration in the ascending colon. Conclusion. UC activity must be included in the differential diagnosis of FUO in patients with longstanding disease, since fever may present alone, with no other manifestations. |
| format | Article |
| id | doaj-art-4616c22abf7746419aecd7b9fc759a24 |
| institution | Kabale University |
| issn | 1687-9627 1687-9635 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-4616c22abf7746419aecd7b9fc759a242025-02-03T07:26:07ZengWileyCase Reports in Medicine1687-96271687-96352016-01-01201610.1155/2016/43962564396256Ulcerative Colitis Activity Presenting as Fever of Unknown Origin, in a Patient with Longstanding Disease under Continuous Treatment with MesalazinePanagiota Voukelatou0Elissavet Sfendouraki1Theodoros Karianos2Sofia Saranti3Dimitrios Tsitsimelis4Ioannis Vrettos5Andreas Kalliakmanis62nd Department of Internal Medicine, General Oncological Hospital of Kifissia “Ag. Anargyroi”, Kifissia, 145 64 Athens, Greece2nd Department of Internal Medicine, General Oncological Hospital of Kifissia “Ag. Anargyroi”, Kifissia, 145 64 Athens, GreeceDepartment of Nuclear Medicine, General Oncological Hospital of Kifissia “Ag. Anargyroi”, Kifissia, 145 64 Athens, GreeceDepartment of Nuclear Medicine, General Oncological Hospital of Kifissia “Ag. Anargyroi”, Kifissia, 145 64 Athens, GreeceDepartment of Radiology, General Oncological Hospital of Kifissia “Ag. Anargyroi”, Kifissia, 145 64 Athens, Greece2nd Department of Internal Medicine, General Oncological Hospital of Kifissia “Ag. Anargyroi”, Kifissia, 145 64 Athens, Greece2nd Department of Internal Medicine, General Oncological Hospital of Kifissia “Ag. Anargyroi”, Kifissia, 145 64 Athens, GreeceBackground. The presence of ulcerative colitis (UC) with no bowel symptoms, as fever of unknown origin (FUO), is uncommon. Objective. To describe the case of an 80-year-old woman who presented with fever, with a history of UC under treatment with mesalazine. Case Presentation. She was admitted due to fever lasting for 12 days with no associated symptoms. Seven years earlier, she was diagnosed with UC. After an extended workup for FUO that failed to reach the diagnosis, she underwent a gallium-67 scintigraphy. This revealed a persistent diffuse concentration of gallium-67 in the ascending colon at 24-hour imaging that remained stable at 48- and 72-hour imaging without any topographic change after the use of laxatives. Considering the results and in the absence of another diagnosis, the patient was treated with 30 mg prednisone daily and mesalazine, as treatment of active UC. Subsequently, the patient’s condition improved markedly and the fever retreated. One month later, she was reevaluated with a gallium-67 scintigraphy with total absence of gallium-67 concentration in the ascending colon. Conclusion. UC activity must be included in the differential diagnosis of FUO in patients with longstanding disease, since fever may present alone, with no other manifestations.http://dx.doi.org/10.1155/2016/4396256 |
| spellingShingle | Panagiota Voukelatou Elissavet Sfendouraki Theodoros Karianos Sofia Saranti Dimitrios Tsitsimelis Ioannis Vrettos Andreas Kalliakmanis Ulcerative Colitis Activity Presenting as Fever of Unknown Origin, in a Patient with Longstanding Disease under Continuous Treatment with Mesalazine Case Reports in Medicine |
| title | Ulcerative Colitis Activity Presenting as Fever of Unknown Origin, in a Patient with Longstanding Disease under Continuous Treatment with Mesalazine |
| title_full | Ulcerative Colitis Activity Presenting as Fever of Unknown Origin, in a Patient with Longstanding Disease under Continuous Treatment with Mesalazine |
| title_fullStr | Ulcerative Colitis Activity Presenting as Fever of Unknown Origin, in a Patient with Longstanding Disease under Continuous Treatment with Mesalazine |
| title_full_unstemmed | Ulcerative Colitis Activity Presenting as Fever of Unknown Origin, in a Patient with Longstanding Disease under Continuous Treatment with Mesalazine |
| title_short | Ulcerative Colitis Activity Presenting as Fever of Unknown Origin, in a Patient with Longstanding Disease under Continuous Treatment with Mesalazine |
| title_sort | ulcerative colitis activity presenting as fever of unknown origin in a patient with longstanding disease under continuous treatment with mesalazine |
| url | http://dx.doi.org/10.1155/2016/4396256 |
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