Lateral Ventricular Volume Asymmetry and Optic Nerve Sheath Diameter Predict Intracranial Pressure in Traumatic Brain Injury Patients
Background. Various noninvasive methods of intracranial pressure (ICP) measurement have been proposed. Each has unique advantages and limitations. This study was aimed at investigating the relationships between lateral ventricular asymmetry on admission computed tomography, optic nerve sheath diamet...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2022-01-01
|
| Series: | Applied Bionics and Biomechanics |
| Online Access: | http://dx.doi.org/10.1155/2022/9808334 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832553459610550272 |
|---|---|
| author | Yang Wang Ziming Yuan Zuoyan Zhang Jiawei Shang Mingna Li Wei Wang |
| author_facet | Yang Wang Ziming Yuan Zuoyan Zhang Jiawei Shang Mingna Li Wei Wang |
| author_sort | Yang Wang |
| collection | DOAJ |
| description | Background. Various noninvasive methods of intracranial pressure (ICP) measurement have been proposed. Each has unique advantages and limitations. This study was aimed at investigating the relationships between lateral ventricular asymmetry on admission computed tomography, optic nerve sheath diameter (ONSD), and ICP in traumatic brain injury (TBI) patients. Methods. A prospective observational study was conducted in the patients admitted to our department between October 2018 and October 2020. 20 patients with moderate-severe TBI with a Glasgow Coma Scale of 3–12 were enrolled. Lateral ventricle volume (LVV) value measurements were conducted using ITK-SNAP software. The lateral ventricular volume ratio (LVR) was quantified by dividing the larger LVV by the smaller. Results. ONSD and LVR had a good correlation with ICP. Admission LVR of >1.735 was shown to have a sensitivity of 90.9% and a specificity of 88.9% for prediction of ICP increase (AUC=0.879; standard error=0.091; 95% CI=0.701 to 1.0; significance level p<0.004). Admission ONSD of >5.55 mm was shown to have a sensitivity of 81.8% and a specificity of 88.9% for prediction of ICP increase (AUC=0.919; standard error=0.062; 95% CI=0.798 to 1.0; significance level p<0.002). Combining the ONSD and LVR, the sensitivity could be improved to 90.9% in parallel test, and the specificity could be improved to 100% in serial test. Conclusion. ONSD and LVR measurements can diagnose elevated ICP in traumatic brain injury patients. ONSD combining with LVR may further improve the diagnostic evaluation. |
| format | Article |
| id | doaj-art-45fed6179bc04cedac2fa57a7c6ad5b1 |
| institution | Kabale University |
| issn | 1754-2103 |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Applied Bionics and Biomechanics |
| spelling | doaj-art-45fed6179bc04cedac2fa57a7c6ad5b12025-02-03T05:53:51ZengWileyApplied Bionics and Biomechanics1754-21032022-01-01202210.1155/2022/9808334Lateral Ventricular Volume Asymmetry and Optic Nerve Sheath Diameter Predict Intracranial Pressure in Traumatic Brain Injury PatientsYang Wang0Ziming Yuan1Zuoyan Zhang2Jiawei Shang3Mingna Li4Wei Wang5Department of Critical Care MedicineDepartment of Critical Care MedicineDepartment of Critical Care MedicineDepartment of Critical Care MedicineDepartment of Critical Care MedicineDepartment of Critical Care MedicineBackground. Various noninvasive methods of intracranial pressure (ICP) measurement have been proposed. Each has unique advantages and limitations. This study was aimed at investigating the relationships between lateral ventricular asymmetry on admission computed tomography, optic nerve sheath diameter (ONSD), and ICP in traumatic brain injury (TBI) patients. Methods. A prospective observational study was conducted in the patients admitted to our department between October 2018 and October 2020. 20 patients with moderate-severe TBI with a Glasgow Coma Scale of 3–12 were enrolled. Lateral ventricle volume (LVV) value measurements were conducted using ITK-SNAP software. The lateral ventricular volume ratio (LVR) was quantified by dividing the larger LVV by the smaller. Results. ONSD and LVR had a good correlation with ICP. Admission LVR of >1.735 was shown to have a sensitivity of 90.9% and a specificity of 88.9% for prediction of ICP increase (AUC=0.879; standard error=0.091; 95% CI=0.701 to 1.0; significance level p<0.004). Admission ONSD of >5.55 mm was shown to have a sensitivity of 81.8% and a specificity of 88.9% for prediction of ICP increase (AUC=0.919; standard error=0.062; 95% CI=0.798 to 1.0; significance level p<0.002). Combining the ONSD and LVR, the sensitivity could be improved to 90.9% in parallel test, and the specificity could be improved to 100% in serial test. Conclusion. ONSD and LVR measurements can diagnose elevated ICP in traumatic brain injury patients. ONSD combining with LVR may further improve the diagnostic evaluation.http://dx.doi.org/10.1155/2022/9808334 |
| spellingShingle | Yang Wang Ziming Yuan Zuoyan Zhang Jiawei Shang Mingna Li Wei Wang Lateral Ventricular Volume Asymmetry and Optic Nerve Sheath Diameter Predict Intracranial Pressure in Traumatic Brain Injury Patients Applied Bionics and Biomechanics |
| title | Lateral Ventricular Volume Asymmetry and Optic Nerve Sheath Diameter Predict Intracranial Pressure in Traumatic Brain Injury Patients |
| title_full | Lateral Ventricular Volume Asymmetry and Optic Nerve Sheath Diameter Predict Intracranial Pressure in Traumatic Brain Injury Patients |
| title_fullStr | Lateral Ventricular Volume Asymmetry and Optic Nerve Sheath Diameter Predict Intracranial Pressure in Traumatic Brain Injury Patients |
| title_full_unstemmed | Lateral Ventricular Volume Asymmetry and Optic Nerve Sheath Diameter Predict Intracranial Pressure in Traumatic Brain Injury Patients |
| title_short | Lateral Ventricular Volume Asymmetry and Optic Nerve Sheath Diameter Predict Intracranial Pressure in Traumatic Brain Injury Patients |
| title_sort | lateral ventricular volume asymmetry and optic nerve sheath diameter predict intracranial pressure in traumatic brain injury patients |
| url | http://dx.doi.org/10.1155/2022/9808334 |
| work_keys_str_mv | AT yangwang lateralventricularvolumeasymmetryandopticnervesheathdiameterpredictintracranialpressureintraumaticbraininjurypatients AT zimingyuan lateralventricularvolumeasymmetryandopticnervesheathdiameterpredictintracranialpressureintraumaticbraininjurypatients AT zuoyanzhang lateralventricularvolumeasymmetryandopticnervesheathdiameterpredictintracranialpressureintraumaticbraininjurypatients AT jiaweishang lateralventricularvolumeasymmetryandopticnervesheathdiameterpredictintracranialpressureintraumaticbraininjurypatients AT mingnali lateralventricularvolumeasymmetryandopticnervesheathdiameterpredictintracranialpressureintraumaticbraininjurypatients AT weiwang lateralventricularvolumeasymmetryandopticnervesheathdiameterpredictintracranialpressureintraumaticbraininjurypatients |