Cancer-associated thoracic aorta arterial thrombosis: case report and review of the literature
BackgroundArterial thrombosis is an uncommon complication in cancer patients, often overshadowed by venous thromboembolic events. Its occurrence in patients with solid tumors on active antineoplastic treatment poses a significant clinical challenge.Key clinical questionGiven the lack of consensus on...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2025-01-01
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| Series: | Frontiers in Cardiovascular Medicine |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fcvm.2025.1480310/full |
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| author | Miguel Borregón María Valero Asia Ferrández Álvaro Muñoz Carmen Roque Javier-David Benítez-Fuentes |
| author_facet | Miguel Borregón María Valero Asia Ferrández Álvaro Muñoz Carmen Roque Javier-David Benítez-Fuentes |
| author_sort | Miguel Borregón |
| collection | DOAJ |
| description | BackgroundArterial thrombosis is an uncommon complication in cancer patients, often overshadowed by venous thromboembolic events. Its occurrence in patients with solid tumors on active antineoplastic treatment poses a significant clinical challenge.Key clinical questionGiven the lack of consensus on the optimal therapy for arterial thrombosis in cancer patients, the best practices for managing an aortic thrombus, and the benefit of low molecular weight heparin (LMWH) must be reviewed.Clinical approachWe present the case of a 70-year-old female with stage IVA lung adenocarcinoma who developed an aortic thrombus during chemo-immunotherapy. The thrombus was successfully treated with LMWH, avoiding further complications, and allowing for the continuation of her cancer therapy.ConclusionsThis case highlights the importance of early detection and management of arterial thrombus in cancer patients. LMWH proved effective in resolving the thrombus, underscoring its role in managing such complications. |
| format | Article |
| id | doaj-art-45fe345b954a4b95b0fcba989f1d794e |
| institution | Kabale University |
| issn | 2297-055X |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Cardiovascular Medicine |
| spelling | doaj-art-45fe345b954a4b95b0fcba989f1d794e2025-01-29T06:45:30ZengFrontiers Media S.A.Frontiers in Cardiovascular Medicine2297-055X2025-01-011210.3389/fcvm.2025.14803101480310Cancer-associated thoracic aorta arterial thrombosis: case report and review of the literatureMiguel Borregón0María Valero1Asia Ferrández2Álvaro Muñoz3Carmen Roque4Javier-David Benítez-Fuentes5Department of Medical Oncology, Hospital General Universitario de Elche, FISABIO, Alicante, SpainDepartment of Medical Oncology, Hospital General Universitario de Elche, FISABIO, Alicante, SpainDepartment of Medical Oncology, Hospital General Universitario de Elche, FISABIO, Alicante, SpainDepartment of Medical Oncology, Hospital General Universitario de Elche, FISABIO, Alicante, SpainDepartment of Radiology, Hospital General Universitario de Elche, FISABIO, Alicante, SpainDepartment of Medical Oncology, Hospital General Universitario de Elche, FISABIO, Alicante, SpainBackgroundArterial thrombosis is an uncommon complication in cancer patients, often overshadowed by venous thromboembolic events. Its occurrence in patients with solid tumors on active antineoplastic treatment poses a significant clinical challenge.Key clinical questionGiven the lack of consensus on the optimal therapy for arterial thrombosis in cancer patients, the best practices for managing an aortic thrombus, and the benefit of low molecular weight heparin (LMWH) must be reviewed.Clinical approachWe present the case of a 70-year-old female with stage IVA lung adenocarcinoma who developed an aortic thrombus during chemo-immunotherapy. The thrombus was successfully treated with LMWH, avoiding further complications, and allowing for the continuation of her cancer therapy.ConclusionsThis case highlights the importance of early detection and management of arterial thrombus in cancer patients. LMWH proved effective in resolving the thrombus, underscoring its role in managing such complications.https://www.frontiersin.org/articles/10.3389/fcvm.2025.1480310/fullcancer-associated thrombosis (CAT)venous thromboembolism (VTE)arterial thromboembolism (ATE)low molecular weight heparin (LMWH)small cell lung carcinoma (SCLC) and cisplatin |
| spellingShingle | Miguel Borregón María Valero Asia Ferrández Álvaro Muñoz Carmen Roque Javier-David Benítez-Fuentes Cancer-associated thoracic aorta arterial thrombosis: case report and review of the literature Frontiers in Cardiovascular Medicine cancer-associated thrombosis (CAT) venous thromboembolism (VTE) arterial thromboembolism (ATE) low molecular weight heparin (LMWH) small cell lung carcinoma (SCLC) and cisplatin |
| title | Cancer-associated thoracic aorta arterial thrombosis: case report and review of the literature |
| title_full | Cancer-associated thoracic aorta arterial thrombosis: case report and review of the literature |
| title_fullStr | Cancer-associated thoracic aorta arterial thrombosis: case report and review of the literature |
| title_full_unstemmed | Cancer-associated thoracic aorta arterial thrombosis: case report and review of the literature |
| title_short | Cancer-associated thoracic aorta arterial thrombosis: case report and review of the literature |
| title_sort | cancer associated thoracic aorta arterial thrombosis case report and review of the literature |
| topic | cancer-associated thrombosis (CAT) venous thromboembolism (VTE) arterial thromboembolism (ATE) low molecular weight heparin (LMWH) small cell lung carcinoma (SCLC) and cisplatin |
| url | https://www.frontiersin.org/articles/10.3389/fcvm.2025.1480310/full |
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