Imatinib Resistance in Chronic Myeloid Leukemia Associated with a D363G BCR::ABL1 Kinase Domain Mutation
Acquired resistance to tyrosine kinase inhibitors (TKIs) remains a therapeutic challenge in the treatment of chronic myeloid leukemia (CML). The most studied reason for TKI resistance is the acquisition of mutations within the BCR::ABL1 tyrosine kinase domain (KDM) and of which the majority of which...
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Main Authors: | Stephen E. Langabeer, Stuart Macleod, Úna Bhreathnach, Kamal Fadalla |
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Format: | Article |
Language: | English |
Published: |
Wiley
2023-01-01
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Series: | Case Reports in Hematology |
Online Access: | http://dx.doi.org/10.1155/2023/6673144 |
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