Megaureter

Almost one-quarter of the children referred to a pediatric urologist for obstructive uropathy suffer from an obstructive megaureter. However, not all megaureters are due to obstruction, as some may be the result of reflux and many simply represent a slightly skewed stage of development that can resu...

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Main Authors: Steve J. Hodges, David Werle, Gordon McLorie, Anthony Atala
Format: Article
Language:English
Published: Wiley 2010-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1100/tsw.2010.54
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author Steve J. Hodges
David Werle
Gordon McLorie
Anthony Atala
author_facet Steve J. Hodges
David Werle
Gordon McLorie
Anthony Atala
author_sort Steve J. Hodges
collection DOAJ
description Almost one-quarter of the children referred to a pediatric urologist for obstructive uropathy suffer from an obstructive megaureter. However, not all megaureters are due to obstruction, as some may be the result of reflux and many simply represent a slightly skewed stage of development that can result in a normal urinary tract if observed. As the use of fetal ultrasonography has expanded, the majority of children with megaureters are now diagnosed early in their development, and physicians are faced with the complex task of distinguishing which children need medical intervention and which do not. The surgical treatments of megaureter are well established, relatively simple, and effective if performed in the correct candidates. Therefore, research efforts in this field have recently focused on improving our ability to diagnose clinically relevant obstructive uropathy and examining the developmental causes of megaureter, and how this disorder may be prevented.
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series The Scientific World Journal
spelling doaj-art-45c925ee4ea0452db345e6a0e6c1bd042025-02-03T01:11:58ZengWileyThe Scientific World Journal1537-744X2010-01-011060361210.1100/tsw.2010.54MegaureterSteve J. Hodges0David Werle1Gordon McLorie2Anthony Atala3Department of Urology, Wake Forest University School of Medicine, Winston-Salem, NC, USADepartment of Urology, Wake Forest University School of Medicine, Winston-Salem, NC, USADepartment of Urology, Wake Forest University School of Medicine, Winston-Salem, NC, USADepartment of Urology, Wake Forest University School of Medicine, Winston-Salem, NC, USAAlmost one-quarter of the children referred to a pediatric urologist for obstructive uropathy suffer from an obstructive megaureter. However, not all megaureters are due to obstruction, as some may be the result of reflux and many simply represent a slightly skewed stage of development that can result in a normal urinary tract if observed. As the use of fetal ultrasonography has expanded, the majority of children with megaureters are now diagnosed early in their development, and physicians are faced with the complex task of distinguishing which children need medical intervention and which do not. The surgical treatments of megaureter are well established, relatively simple, and effective if performed in the correct candidates. Therefore, research efforts in this field have recently focused on improving our ability to diagnose clinically relevant obstructive uropathy and examining the developmental causes of megaureter, and how this disorder may be prevented.http://dx.doi.org/10.1100/tsw.2010.54
spellingShingle Steve J. Hodges
David Werle
Gordon McLorie
Anthony Atala
Megaureter
The Scientific World Journal
title Megaureter
title_full Megaureter
title_fullStr Megaureter
title_full_unstemmed Megaureter
title_short Megaureter
title_sort megaureter
url http://dx.doi.org/10.1100/tsw.2010.54
work_keys_str_mv AT stevejhodges megaureter
AT davidwerle megaureter
AT gordonmclorie megaureter
AT anthonyatala megaureter