Crescentic Glomerulonephritis with Anti-GBM and p-ANCA Antibodies

We are presenting a case of renal failure with anti-GBM and p-ANCA antibodies positive. Patients with dual antibodies are considered to be a vasculitis-variant of anti-GBM antibody nephritis. These patients may have atypical presentation and it may delay diagnosis and treatment. Recurrence rate is h...

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Main Authors: Tariq Javed, Parag Vohra
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Case Reports in Nephrology
Online Access:http://dx.doi.org/10.1155/2012/132085
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author Tariq Javed
Parag Vohra
author_facet Tariq Javed
Parag Vohra
author_sort Tariq Javed
collection DOAJ
description We are presenting a case of renal failure with anti-GBM and p-ANCA antibodies positive. Patients with dual antibodies are considered to be a vasculitis-variant of anti-GBM antibody nephritis. These patients may have atypical presentation and it may delay diagnosis and treatment. Recurrence rate is higher in these patients. We reviewed the literature of cases and studies on cresenteric glomerulonephritis with anti-GBM and p-ANCA positive patients. We recommend that patients suspected with pulmonary-renal syndrome should be checked for anti-GBM and p-ANCA antibodies, should undergo renal biopsy and should should have close long term follow up to watch for recurrence.
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institution Kabale University
issn 2090-6641
2090-665X
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series Case Reports in Nephrology
spelling doaj-art-45ac431a011d43ffafbb1b0d330f4a2a2025-02-03T06:42:08ZengWileyCase Reports in Nephrology2090-66412090-665X2012-01-01201210.1155/2012/132085132085Crescentic Glomerulonephritis with Anti-GBM and p-ANCA AntibodiesTariq Javed0Parag Vohra1Department of Medicine, Bakersfield Memorial Hospital, Bakersfield, CA 93301, USADepartment of Medicine, Bakersfield Memorial Hospital, Bakersfield, CA 93301, USAWe are presenting a case of renal failure with anti-GBM and p-ANCA antibodies positive. Patients with dual antibodies are considered to be a vasculitis-variant of anti-GBM antibody nephritis. These patients may have atypical presentation and it may delay diagnosis and treatment. Recurrence rate is higher in these patients. We reviewed the literature of cases and studies on cresenteric glomerulonephritis with anti-GBM and p-ANCA positive patients. We recommend that patients suspected with pulmonary-renal syndrome should be checked for anti-GBM and p-ANCA antibodies, should undergo renal biopsy and should should have close long term follow up to watch for recurrence.http://dx.doi.org/10.1155/2012/132085
spellingShingle Tariq Javed
Parag Vohra
Crescentic Glomerulonephritis with Anti-GBM and p-ANCA Antibodies
Case Reports in Nephrology
title Crescentic Glomerulonephritis with Anti-GBM and p-ANCA Antibodies
title_full Crescentic Glomerulonephritis with Anti-GBM and p-ANCA Antibodies
title_fullStr Crescentic Glomerulonephritis with Anti-GBM and p-ANCA Antibodies
title_full_unstemmed Crescentic Glomerulonephritis with Anti-GBM and p-ANCA Antibodies
title_short Crescentic Glomerulonephritis with Anti-GBM and p-ANCA Antibodies
title_sort crescentic glomerulonephritis with anti gbm and p anca antibodies
url http://dx.doi.org/10.1155/2012/132085
work_keys_str_mv AT tariqjaved crescenticglomerulonephritiswithantigbmandpancaantibodies
AT paragvohra crescenticglomerulonephritiswithantigbmandpancaantibodies