Antifungal Activity of Coumarin Mammeisin Isolated from Species of the Kielmeyera Genre (Family: Clusiaceae or Guttiferae)
Coumarin mammeisin isolated from Kielmeyera elata was evaluated for its toxicity and antifungal activities. The toxicity of mammeisin was investigated by utilizing the Artemia salina methodology to determine its LD50 value. The minimum inhibitory concentration (MIC) of fungi Candida sp. was assessed...
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2015/241243 |
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| author | Helcio Cassemiro Marcondes Tânia T. de Oliveira Jason G. Taylor Moisés Hamoy Arman do Leonel Neto Vanessa Joia de Mello Tanus J. Nagem |
| author_facet | Helcio Cassemiro Marcondes Tânia T. de Oliveira Jason G. Taylor Moisés Hamoy Arman do Leonel Neto Vanessa Joia de Mello Tanus J. Nagem |
| author_sort | Helcio Cassemiro Marcondes |
| collection | DOAJ |
| description | Coumarin mammeisin isolated from Kielmeyera elata was evaluated for its toxicity and antifungal activities. The toxicity of mammeisin was investigated by utilizing the Artemia salina methodology to determine its LD50 value. The minimum inhibitory concentration (MIC) of fungi Candida sp. was assessed for mammeisin, presenting equivalent activity to ketoconazole but displaying better results than fluconazole. |
| format | Article |
| id | doaj-art-45963f0934a14575a8741e23f1c42a6c |
| institution | Kabale University |
| issn | 2090-9063 2090-9071 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Chemistry |
| spelling | doaj-art-45963f0934a14575a8741e23f1c42a6c2025-02-03T06:11:31ZengWileyJournal of Chemistry2090-90632090-90712015-01-01201510.1155/2015/241243241243Antifungal Activity of Coumarin Mammeisin Isolated from Species of the Kielmeyera Genre (Family: Clusiaceae or Guttiferae)Helcio Cassemiro Marcondes0Tânia T. de Oliveira1Jason G. Taylor2Moisés Hamoy3Arman do Leonel Neto4Vanessa Joia de Mello5Tanus J. Nagem6Chemistry Department, Federal University of Ouro Preto, Morro do Cruzeiro, 34500-000 Ouro Preto, MG, BrazilDepartment of Biochemistry, Federal University of Viçosa, 36570-900 Viçosa, MG, BrazilChemistry Department, Federal University of Ouro Preto, Morro do Cruzeiro, 34500-000 Ouro Preto, MG, BrazilInstitute of Biological Sciences, Federal University of Pará, 66075-110 Belém, PA, BrazilChemistry Department, Federal University of Ouro Preto, Morro do Cruzeiro, 34500-000 Ouro Preto, MG, BrazilInstitute of Biological Sciences, Federal University of Pará, 66075-110 Belém, PA, BrazilChemistry Department, Federal University of Ouro Preto, Morro do Cruzeiro, 34500-000 Ouro Preto, MG, BrazilCoumarin mammeisin isolated from Kielmeyera elata was evaluated for its toxicity and antifungal activities. The toxicity of mammeisin was investigated by utilizing the Artemia salina methodology to determine its LD50 value. The minimum inhibitory concentration (MIC) of fungi Candida sp. was assessed for mammeisin, presenting equivalent activity to ketoconazole but displaying better results than fluconazole.http://dx.doi.org/10.1155/2015/241243 |
| spellingShingle | Helcio Cassemiro Marcondes Tânia T. de Oliveira Jason G. Taylor Moisés Hamoy Arman do Leonel Neto Vanessa Joia de Mello Tanus J. Nagem Antifungal Activity of Coumarin Mammeisin Isolated from Species of the Kielmeyera Genre (Family: Clusiaceae or Guttiferae) Journal of Chemistry |
| title | Antifungal Activity of Coumarin Mammeisin Isolated from Species of the Kielmeyera Genre (Family: Clusiaceae or Guttiferae) |
| title_full | Antifungal Activity of Coumarin Mammeisin Isolated from Species of the Kielmeyera Genre (Family: Clusiaceae or Guttiferae) |
| title_fullStr | Antifungal Activity of Coumarin Mammeisin Isolated from Species of the Kielmeyera Genre (Family: Clusiaceae or Guttiferae) |
| title_full_unstemmed | Antifungal Activity of Coumarin Mammeisin Isolated from Species of the Kielmeyera Genre (Family: Clusiaceae or Guttiferae) |
| title_short | Antifungal Activity of Coumarin Mammeisin Isolated from Species of the Kielmeyera Genre (Family: Clusiaceae or Guttiferae) |
| title_sort | antifungal activity of coumarin mammeisin isolated from species of the kielmeyera genre family clusiaceae or guttiferae |
| url | http://dx.doi.org/10.1155/2015/241243 |
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