Tumor-associated macrophage-derived exosome miR-194 confers cisplatin resistance in GC cells
Abstract Objective At all stages of gastric cancer (GC), cisplatin is the first-line chemotherapeutic agent, but its efficacy remains limited, with a response rate of less than 20%, largely because of resistance to the drug. It aims to determine whether macrophage-derived exosomes are involved in th...
Saved in:
Main Authors: | Yi Zhou, Yang-cheng Sun, Qiong-yan Zhang, Jing Wang, Xian-ya Zhu, Xiang-yu Su |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2025-02-01
|
Series: | European Journal of Medical Research |
Subjects: | |
Online Access: | https://doi.org/10.1186/s40001-025-02329-5 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
The MIR181A2HG/miR‐5680/VCAN‐CD44 Axis Regulates Gastric Cancer Lymph Node Metastasis by Promoting M2 Macrophage Polarization
by: Weijie Zang, et al.
Published: (2025-01-01) -
Pyrogallol acts as a novel anticancer factor to enhance the sensitivity to cisplatin in ovarian cancer cells through inducing miR-15a upregulation
by: Azin Shirani, et al.
Published: (2025-01-01) -
M2-like macrophage-derived exosomes inhibit osteoclastogenesis via releasing miR-1227-5p
by: Shan Chen, et al.
Published: (2025-01-01) -
Biochemical analysis of miR-217 and miR-532 in patients with fibromyalgia
by: Shymaa E. Ayoub, et al.
Published: (2025-02-01) -
Exosomal miR-122 derived from M2 macrophages induces osteogenic differentiation of bone marrow mesenchymal stem cells in the treatment of alcoholic osteonecrosis of the femoral head
by: Guoping Le, et al.
Published: (2025-01-01)