A Novel Approach for Objective Assessment of White Blood Cells Using Computational Vision Algorithms

In the field of medicine, the analysis of blood is one of the most important exams to determine the physiological state of a patient. In the analysis of the blood sample, an important process is the counting and classification of white blood cells, which is done manually, being an exhaustive, subjec...

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Main Authors: Cesar Mauricio Rodríguez Barrero, Lyle Alberto Romero Gabalan, Edgar Eduardo Roa Guerrero
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Advances in Hematology
Online Access:http://dx.doi.org/10.1155/2018/4716370
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author Cesar Mauricio Rodríguez Barrero
Lyle Alberto Romero Gabalan
Edgar Eduardo Roa Guerrero
author_facet Cesar Mauricio Rodríguez Barrero
Lyle Alberto Romero Gabalan
Edgar Eduardo Roa Guerrero
author_sort Cesar Mauricio Rodríguez Barrero
collection DOAJ
description In the field of medicine, the analysis of blood is one of the most important exams to determine the physiological state of a patient. In the analysis of the blood sample, an important process is the counting and classification of white blood cells, which is done manually, being an exhaustive, subjective, and error-prone activity due to the physical fatigue that generates the professional because it is a method that consumes long laxes of time. The purpose of the research was to develop a system to identify and classify blood cells, by the implementation of the networks of Gaussian radial base functions (RBFN) for the extraction of its nucleus and subsequently their classification through the morphological characteristics, its color, and the distance between objects. Finally, the results obtained with the validation through the coefficient of determination showed an overall accuracy of 97.9% in the classification of the white blood cells per individual, while the precision in the classification by type of cell evidenced results in 93.4% for lymphocytes, 97.37% for monocytes, 79.5% for neutrophils, 73.07% for eosinophils, and a 100% in basophils with respect to the professional. In this way, the proposed system becomes a reliable technological support that contributes to the improvement of the analysis for identification of blood cells and therefore would benefit the low-level hematology establishments as well as to the processes of research in the area of medicine.
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issn 1687-9104
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publishDate 2018-01-01
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spelling doaj-art-457205f557fe4ec58757d29d065687e72025-02-03T01:28:53ZengWileyAdvances in Hematology1687-91041687-91122018-01-01201810.1155/2018/47163704716370A Novel Approach for Objective Assessment of White Blood Cells Using Computational Vision AlgorithmsCesar Mauricio Rodríguez Barrero0Lyle Alberto Romero Gabalan1Edgar Eduardo Roa Guerrero2KINESTASIS Seedlings of Research, University of Cundinamarca, Fusagasugá, ColombiaKINESTASIS Seedlings of Research, University of Cundinamarca, Fusagasugá, ColombiaKINESTASIS Seedlings of Research, University of Cundinamarca, Fusagasugá, ColombiaIn the field of medicine, the analysis of blood is one of the most important exams to determine the physiological state of a patient. In the analysis of the blood sample, an important process is the counting and classification of white blood cells, which is done manually, being an exhaustive, subjective, and error-prone activity due to the physical fatigue that generates the professional because it is a method that consumes long laxes of time. The purpose of the research was to develop a system to identify and classify blood cells, by the implementation of the networks of Gaussian radial base functions (RBFN) for the extraction of its nucleus and subsequently their classification through the morphological characteristics, its color, and the distance between objects. Finally, the results obtained with the validation through the coefficient of determination showed an overall accuracy of 97.9% in the classification of the white blood cells per individual, while the precision in the classification by type of cell evidenced results in 93.4% for lymphocytes, 97.37% for monocytes, 79.5% for neutrophils, 73.07% for eosinophils, and a 100% in basophils with respect to the professional. In this way, the proposed system becomes a reliable technological support that contributes to the improvement of the analysis for identification of blood cells and therefore would benefit the low-level hematology establishments as well as to the processes of research in the area of medicine.http://dx.doi.org/10.1155/2018/4716370
spellingShingle Cesar Mauricio Rodríguez Barrero
Lyle Alberto Romero Gabalan
Edgar Eduardo Roa Guerrero
A Novel Approach for Objective Assessment of White Blood Cells Using Computational Vision Algorithms
Advances in Hematology
title A Novel Approach for Objective Assessment of White Blood Cells Using Computational Vision Algorithms
title_full A Novel Approach for Objective Assessment of White Blood Cells Using Computational Vision Algorithms
title_fullStr A Novel Approach for Objective Assessment of White Blood Cells Using Computational Vision Algorithms
title_full_unstemmed A Novel Approach for Objective Assessment of White Blood Cells Using Computational Vision Algorithms
title_short A Novel Approach for Objective Assessment of White Blood Cells Using Computational Vision Algorithms
title_sort novel approach for objective assessment of white blood cells using computational vision algorithms
url http://dx.doi.org/10.1155/2018/4716370
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