Unveiling the role of melatonin‐related gene CSNK1D in osteoclastogenesis and its implications for osteoporosis treatment

Unveiling the role of melatonin‐related gene CSNK1D in osteoclastogenesis and its implications for osteoporosis treatment

Abstract Osteoporosis (OP) is a prevalent bone disease characterized by reduced bone density and quality, increasing fragility and fracture risk. Osteoclast (OC) activity and circadian rhythm play a role in the pathogenesis of OP. Melatonin is a circadian regulator that affects bone metabolism, but...

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Bibliographic Details
Main Authors: Jiewen Zhang, Shaobo Wu, Fangze Xing, Ning Kong, Yiwei Zhao, Xudong Duan, Yiyang Li, Kunzheng Wang, Run Tian, Pei Yang
Format: Article
Language:English
Published: Wiley 2025-02-01
Series:Experimental Physiology
Subjects:
circadian rhythm
CSNK1D
melatonin
osteoclast
osteoporosis
Online Access:https://doi.org/10.1113/EP092189
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