Nanopore-based random genomic sampling for intraoperative molecular diagnosis

Nanopore-based random genomic sampling for intraoperative molecular diagnosis

Abstract Background Central nervous system tumors are among the most lethal types of cancer. A critical factor for tailored neurosurgical resection strategies depends on specific tumor types. However, it is uncommon to have a preoperative tumor diagnosis, and intraoperative morphology-based diagnosi...

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Bibliographic Details
Main Authors: Francesco E. Emiliani, Abdol Aziz Ould Ismail, Edward G. Hughes, Gregory J. Tsongalis, George J. Zanazzi, Chun-Chieh Lin
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Genome Medicine
Subjects:
Nanopore sequencing
Copy number variation
Methylation classification
Intraoperative diagnosis
Online Access:https://doi.org/10.1186/s13073-025-01427-7
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