Bioinformatics combining machine learning and single-cell sequencing analysis to identify common mechanisms and biomarkers of rheumatoid arthritis and ischemic heart failure

Bioinformatics combining machine learning and single-cell sequencing analysis to identify common mechanisms and biomarkers of rheumatoid arthritis and ischemic heart failure

Patients with rheumatoid arthritis (RA) have an increased risk of ischemic heart failure (IHF), but the shared mechanisms are unclear. This study analyzed RNA sequencing data from five RA and IHF datasets to identify common biological mechanisms and significant biomarkers. One hundred and seventy-se...

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Bibliographic Details
Main Authors: Ziyi Sun, Jianguo Lin, Xiaoning Sun, Zhangjun Yun, Xiaoxiao Zhang, Siyu Xu, Jinlong Duan, Kuiwu Yao
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Heliyon
Subjects:
Rheumatoid arthritis
Ischemic heart failure
Microarray
Machine learning
Single-cell
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844025000209
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