Cannabidiol Mediates Beneficial Effects on the Microvasculature of Murine Hearts with Regard to Irradiation-Induced Inflammation and Early Signs of Fibrosis

Cannabidiol Mediates Beneficial Effects on the Microvasculature of Murine Hearts with Regard to Irradiation-Induced Inflammation and Early Signs of Fibrosis

Objective: Radiotherapy administered to control thoracic cancers results in a partial irradiation of the heart at mean doses up to 19 Gy, which increases the risk of developing a spectrum of cardiovascular diseases known as radiation-induced heart disease (RIHD). As inflammation is a major driver of...

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Bibliographic Details
Main Authors: Lisa Bauer, Bayan Alkotub, Markus Ballmann, Khouloud Hachani, Mengyao Jin, Morteza Hasanzadeh Kafshgari, Gerhard Rammes, Alan Graham Pockley, Gabriele Multhoff
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Radiation
Subjects:
radiotherapy
cannabidiol (CBD)
irradiation-induced heart disease
vascular inflammation
fibrosis
Online Access:https://www.mdpi.com/2673-592X/5/2/17
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