Heritability and polygenic load for comorbid anxiety and depression

Abstract Anxiety and depression commonly occur together resulting in worse health outcomes than when they occur in isolation. We aimed to determine whether the genetic liability for comorbid anxiety and depression was greater than when anxiety or depression occurred alone. Data from 12,792 genotyped...

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Main Authors: Fara Tabrizi, Jörgen Rosén, Hampus Grönvall, Victor Rahimzadeh William-Olsson, Erik Arner, Patrik KE Magnusson, Camilla Palm, Henrik Larsson, Alexander Viktorin, Jens Bernhardsson, Johanna Björkdahl, Billy Jansson, Örjan Sundin, Xuan Zhou, Doug Speed, Fredrik Åhs
Format: Article
Language:English
Published: Nature Publishing Group 2025-03-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-025-03325-3
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