Role of PLA2R domain antibodies and epitope spreading in risk stratification and prediction of proteinuria remission in primary membranous nephropathy

Role of PLA2R domain antibodies and epitope spreading in risk stratification and prediction of proteinuria remission in primary membranous nephropathy

Abstract The clinical significance of phospholipase A2 receptor (PLA2R) antigen domain-specific antibodies has not been determined. We investigated the role of serum PLA2R domain antibodies and epitope spreading in risk stratification and proteinuria remission in primary membranous nephropathy (PMN)...

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Bibliographic Details
Main Authors: Xiran Zhang, Feiya Yang, Yun Fan, Jing Xue, Bin Liu, Zhijian Zhang, Weiwei Shan, Hanzhi Chen, Ting Cai, Leting Zhou, Biao Huang, Liang Wang, Xiaobin Liu
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Scientific Reports
Subjects:
PLA2R domain antibodies
Epitope spreading
Proteinuria remission
Primary membranous nephropathy
Online Access:https://doi.org/10.1038/s41598-025-91366-5
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