Possible Involvement of Smad Signaling Pathways in Induction of Odontoblastic Properties in KN-3 Cells by Bone Morphogenetic Protein-2: A Growth Factor to Induce Dentin Regeneration

Possible Involvement of Smad Signaling Pathways in Induction of Odontoblastic Properties in KN-3 Cells by Bone Morphogenetic Protein-2: A Growth Factor to Induce Dentin Regeneration

We examined the effects of bone morphogenetic protein-2 (BMP-2) on growth, differentiation, and intracellular signaling pathways of odontoblast-like cells, KN-3 cells, to clarify molecular mechanisms of odontoblast differentiation during pulp regeneration process. After treatment with BMP-2, the cel...

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Bibliographic Details
Main Authors: Ayako Washio, Chiaki Kitamura, Takahiko Morotomi, Masamichi Terashita, Tatsuji Nishihara
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:International Journal of Dentistry
Online Access:http://dx.doi.org/10.1155/2012/258469
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