Contribution of gait speed, grip strength, and depression on the risk of serious falls among older adults
Objective: This study assessed the individual and combined associations of slow gait speed, weak grip strength, and depressive symptoms with the risk of serious falls in an aging population. Methods: This study used data from the Aspirin in Reducing Events in the Elderly (ASPREE) trial, which collec...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-06-01
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| Series: | Archives of Gerontology and Geriatrics Plus |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2950307825000372 |
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| author | Temam Beshir Raru Julie A. Pasco Mojtaba Lotfaliany Shiva Ganjali Malcolm Forbes Alice J. Owen Robyn L Woods Anna Barker Suzanne G. Orchard Joanne Ryan John J. McNeil Michael Berk Mohammadreza Mohebbi |
| author_facet | Temam Beshir Raru Julie A. Pasco Mojtaba Lotfaliany Shiva Ganjali Malcolm Forbes Alice J. Owen Robyn L Woods Anna Barker Suzanne G. Orchard Joanne Ryan John J. McNeil Michael Berk Mohammadreza Mohebbi |
| author_sort | Temam Beshir Raru |
| collection | DOAJ |
| description | Objective: This study assessed the individual and combined associations of slow gait speed, weak grip strength, and depressive symptoms with the risk of serious falls in an aging population. Methods: This study used data from the Aspirin in Reducing Events in the Elderly (ASPREE) trial, which collected adjudicated events on serious falls from Australian community-dwelling older adults (≥70 years). Cox proportional hazard models were employed to estimate adjusted hazard ratios (AHR). Results: Of 16,357 participants, 1505 (9.2 %) had serious falls over the median (IQR) follow-up of 4.4 (3.3–5.5) years. Slow gait, weak grip, and depressive symptoms at baseline were associated with serious falls (AHR = 1.38, 95 %CI: 1.22–1.56; AHR = 1.22, 95 %CI: 1.07–1.38, and AHR=1.28, 95 %CI:1.10–1.50, respectively). Combined slow gait, weak grip, and depressive symptoms were associated with a more than two-fold increase in the risk of serious falls (AHR=2.15, 95 %CI: 1.56–2.97). The presence of slow gait and weak grip were associated with a 66 % increase in the risk of serious falls (AHR=1.66, 95 %CI:1.40–1.97). Depressive symptoms worsened the risk of falls among individuals with chronic conditions such as diabetes. Conclusion: Combined gait speed, grip strength, and depressive symptoms have a strong association with serious falls in an aging population. Therefore, incorporating strength and mobility training interventions to improve physical functions and addressing depression through timely diagnosis and effective treatment may help to prevent the risk of falls among older adults. |
| format | Article |
| id | doaj-art-44ffa42dc3214b0b81aad7972fe94de4 |
| institution | Kabale University |
| issn | 2950-3078 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Archives of Gerontology and Geriatrics Plus |
| spelling | doaj-art-44ffa42dc3214b0b81aad7972fe94de42025-08-20T03:48:27ZengElsevierArchives of Gerontology and Geriatrics Plus2950-30782025-06-012210015510.1016/j.aggp.2025.100155Contribution of gait speed, grip strength, and depression on the risk of serious falls among older adultsTemam Beshir Raru0Julie A. Pasco1Mojtaba Lotfaliany2Shiva Ganjali3Malcolm Forbes4Alice J. Owen5Robyn L Woods6Anna Barker7Suzanne G. Orchard8Joanne Ryan9John J. McNeil10Michael Berk11Mohammadreza Mohebbi12Deakin University, the Institute for Mental and Physical Health and Clinical Translation (IMPACT), School of Medicine, Barwon Health, Geelong, Victoria, Australia; School of Public Health, College of Health and Medical Sciences, Haramaya University, Harar, Ethiopia; Corresponding author at: The Institute for Mental and Physical Health and Clinical Translation (IMPACT), School of Medicine, Deakin University, PO Box 281, Geelong, VIC 3220, Australia.Deakin University, the Institute for Mental and Physical Health and Clinical Translation (IMPACT), School of Medicine, Barwon Health, Geelong, Victoria, Australia; School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia; Department of Medicine, The University of Melbourne – Western Health, St Albans, AustraliaDeakin University, the Institute for Mental and Physical Health and Clinical Translation (IMPACT), School of Medicine, Barwon Health, Geelong, Victoria, AustraliaDeakin University, the Institute for Mental and Physical Health and Clinical Translation (IMPACT), School of Medicine, Barwon Health, Geelong, Victoria, AustraliaDeakin University, the Institute for Mental and Physical Health and Clinical Translation (IMPACT), School of Medicine, Barwon Health, Geelong, Victoria, AustraliaSchool of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, AustraliaSchool of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, AustraliaSchool of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, AustraliaSchool of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, AustraliaSchool of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, AustraliaSchool of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, AustraliaDeakin University, the Institute for Mental and Physical Health and Clinical Translation (IMPACT), School of Medicine, Barwon Health, Geelong, Victoria, AustraliaDeakin University, the Institute for Mental and Physical Health and Clinical Translation (IMPACT), School of Medicine, Barwon Health, Geelong, Victoria, Australia; Biostatistics Unit, Faculty of Health, Deakin University, Geelong, Vitoria, AustraliaObjective: This study assessed the individual and combined associations of slow gait speed, weak grip strength, and depressive symptoms with the risk of serious falls in an aging population. Methods: This study used data from the Aspirin in Reducing Events in the Elderly (ASPREE) trial, which collected adjudicated events on serious falls from Australian community-dwelling older adults (≥70 years). Cox proportional hazard models were employed to estimate adjusted hazard ratios (AHR). Results: Of 16,357 participants, 1505 (9.2 %) had serious falls over the median (IQR) follow-up of 4.4 (3.3–5.5) years. Slow gait, weak grip, and depressive symptoms at baseline were associated with serious falls (AHR = 1.38, 95 %CI: 1.22–1.56; AHR = 1.22, 95 %CI: 1.07–1.38, and AHR=1.28, 95 %CI:1.10–1.50, respectively). Combined slow gait, weak grip, and depressive symptoms were associated with a more than two-fold increase in the risk of serious falls (AHR=2.15, 95 %CI: 1.56–2.97). The presence of slow gait and weak grip were associated with a 66 % increase in the risk of serious falls (AHR=1.66, 95 %CI:1.40–1.97). Depressive symptoms worsened the risk of falls among individuals with chronic conditions such as diabetes. Conclusion: Combined gait speed, grip strength, and depressive symptoms have a strong association with serious falls in an aging population. Therefore, incorporating strength and mobility training interventions to improve physical functions and addressing depression through timely diagnosis and effective treatment may help to prevent the risk of falls among older adults.http://www.sciencedirect.com/science/article/pii/S2950307825000372Serious fallsGait speedGrip strengthDepressive symptoms |
| spellingShingle | Temam Beshir Raru Julie A. Pasco Mojtaba Lotfaliany Shiva Ganjali Malcolm Forbes Alice J. Owen Robyn L Woods Anna Barker Suzanne G. Orchard Joanne Ryan John J. McNeil Michael Berk Mohammadreza Mohebbi Contribution of gait speed, grip strength, and depression on the risk of serious falls among older adults Archives of Gerontology and Geriatrics Plus Serious falls Gait speed Grip strength Depressive symptoms |
| title | Contribution of gait speed, grip strength, and depression on the risk of serious falls among older adults |
| title_full | Contribution of gait speed, grip strength, and depression on the risk of serious falls among older adults |
| title_fullStr | Contribution of gait speed, grip strength, and depression on the risk of serious falls among older adults |
| title_full_unstemmed | Contribution of gait speed, grip strength, and depression on the risk of serious falls among older adults |
| title_short | Contribution of gait speed, grip strength, and depression on the risk of serious falls among older adults |
| title_sort | contribution of gait speed grip strength and depression on the risk of serious falls among older adults |
| topic | Serious falls Gait speed Grip strength Depressive symptoms |
| url | http://www.sciencedirect.com/science/article/pii/S2950307825000372 |
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