Exploration of Nitrate Reductase Metabolic Pathway in Corynebacterium pseudotuberculosis
Based on the ability of nitrate reductase synthesis, Corynebacterium pseudotuberculosis is classified into two biovars: Ovis and Equi. Due to the presence of nitrate reductase, the Equi biovar can survive in absence of oxygen. On the other hand, Ovis biovar that does not have nitrate reductase is ab...
Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2017-01-01
|
| Series: | International Journal of Genomics |
| Online Access: | http://dx.doi.org/10.1155/2017/9481756 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832560239390490624 |
|---|---|
| author | Sintia Almeida Cassiana Sousa Vinícius Abreu Carlos Diniz Elaine M. S. Dorneles Andrey P. Lage Debmalya Barh Vasco Azevedo |
| author_facet | Sintia Almeida Cassiana Sousa Vinícius Abreu Carlos Diniz Elaine M. S. Dorneles Andrey P. Lage Debmalya Barh Vasco Azevedo |
| author_sort | Sintia Almeida |
| collection | DOAJ |
| description | Based on the ability of nitrate reductase synthesis, Corynebacterium pseudotuberculosis is classified into two biovars: Ovis and Equi. Due to the presence of nitrate reductase, the Equi biovar can survive in absence of oxygen. On the other hand, Ovis biovar that does not have nitrate reductase is able to adapt to various ecological niches and can grow on certain carbon sources. Apart from these two biovars, some other strains are also able to carry out the reduction of nitrate. The enzymes that are involved in electron transport chain are also identified by in silico methods. Findings about pathogen metabolism can contribute to the identification of relationship between nitrate reductase and the C. pseudotuberculosis pathogenicity, virulence factors, and discovery of drug targets. |
| format | Article |
| id | doaj-art-44dd3ced8d854bd5aa70cafc5a4080b0 |
| institution | Kabale University |
| issn | 2314-436X 2314-4378 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Genomics |
| spelling | doaj-art-44dd3ced8d854bd5aa70cafc5a4080b02025-02-03T01:28:06ZengWileyInternational Journal of Genomics2314-436X2314-43782017-01-01201710.1155/2017/94817569481756Exploration of Nitrate Reductase Metabolic Pathway in Corynebacterium pseudotuberculosisSintia Almeida0Cassiana Sousa1Vinícius Abreu2Carlos Diniz3Elaine M. S. Dorneles4Andrey P. Lage5Debmalya Barh6Vasco Azevedo7Institute of Biologic Sciences, Federal University of Minas Gerais, 31270-901 Belo Horizonte, MG, BrazilInstitute of Biologic Sciences, Federal University of Minas Gerais, 31270-901 Belo Horizonte, MG, BrazilCenter for Nuclear Energy in Agriculture, University of Sao Paulo, 13400-970 Piracicaba, SP, BrazilInstitute of Biologic Sciences, Federal University of Minas Gerais, 31270-901 Belo Horizonte, MG, BrazilEscola de Veterinária, Federal University of Minas Gerais, Belo Horizonte, MG, BrazilEscola de Veterinária, Federal University of Minas Gerais, Belo Horizonte, MG, BrazilCentre for Genomics and Applied Gene Technology, Institute of Integrative Omics and Applied Biotechnology (IIOAB), Nonakuri, Purba Medinipur, West Bengal, IndiaInstitute of Biologic Sciences, Federal University of Minas Gerais, 31270-901 Belo Horizonte, MG, BrazilBased on the ability of nitrate reductase synthesis, Corynebacterium pseudotuberculosis is classified into two biovars: Ovis and Equi. Due to the presence of nitrate reductase, the Equi biovar can survive in absence of oxygen. On the other hand, Ovis biovar that does not have nitrate reductase is able to adapt to various ecological niches and can grow on certain carbon sources. Apart from these two biovars, some other strains are also able to carry out the reduction of nitrate. The enzymes that are involved in electron transport chain are also identified by in silico methods. Findings about pathogen metabolism can contribute to the identification of relationship between nitrate reductase and the C. pseudotuberculosis pathogenicity, virulence factors, and discovery of drug targets.http://dx.doi.org/10.1155/2017/9481756 |
| spellingShingle | Sintia Almeida Cassiana Sousa Vinícius Abreu Carlos Diniz Elaine M. S. Dorneles Andrey P. Lage Debmalya Barh Vasco Azevedo Exploration of Nitrate Reductase Metabolic Pathway in Corynebacterium pseudotuberculosis International Journal of Genomics |
| title | Exploration of Nitrate Reductase Metabolic Pathway in Corynebacterium pseudotuberculosis |
| title_full | Exploration of Nitrate Reductase Metabolic Pathway in Corynebacterium pseudotuberculosis |
| title_fullStr | Exploration of Nitrate Reductase Metabolic Pathway in Corynebacterium pseudotuberculosis |
| title_full_unstemmed | Exploration of Nitrate Reductase Metabolic Pathway in Corynebacterium pseudotuberculosis |
| title_short | Exploration of Nitrate Reductase Metabolic Pathway in Corynebacterium pseudotuberculosis |
| title_sort | exploration of nitrate reductase metabolic pathway in corynebacterium pseudotuberculosis |
| url | http://dx.doi.org/10.1155/2017/9481756 |
| work_keys_str_mv | AT sintiaalmeida explorationofnitratereductasemetabolicpathwayincorynebacteriumpseudotuberculosis AT cassianasousa explorationofnitratereductasemetabolicpathwayincorynebacteriumpseudotuberculosis AT viniciusabreu explorationofnitratereductasemetabolicpathwayincorynebacteriumpseudotuberculosis AT carlosdiniz explorationofnitratereductasemetabolicpathwayincorynebacteriumpseudotuberculosis AT elainemsdorneles explorationofnitratereductasemetabolicpathwayincorynebacteriumpseudotuberculosis AT andreyplage explorationofnitratereductasemetabolicpathwayincorynebacteriumpseudotuberculosis AT debmalyabarh explorationofnitratereductasemetabolicpathwayincorynebacteriumpseudotuberculosis AT vascoazevedo explorationofnitratereductasemetabolicpathwayincorynebacteriumpseudotuberculosis |