Mortality Trends in Patients Hospitalized with the Initial Acute Myocardial Infarction in a Middle Eastern Country over 20 Years
We aimed to define the temporal trend in the initial Acute Myocardial Infarction (AMI) management and outcome during the last two decades in a Middle Eastern country. A total of 10,915 patients were admitted with initial AMI with mean age of 53 ± 11.8 years. Comparing the two decades (1991–2000) to...
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | Cardiology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2014/464323 |
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| author | Emad Ahmed Jassim Al Suwaidi Ayman El-Menyar Hajar A. H. AlBinali Rajvir Singh A. A. Gehani |
| author_facet | Emad Ahmed Jassim Al Suwaidi Ayman El-Menyar Hajar A. H. AlBinali Rajvir Singh A. A. Gehani |
| author_sort | Emad Ahmed |
| collection | DOAJ |
| description | We aimed to define the temporal trend in the initial Acute Myocardial Infarction (AMI) management and outcome during the last two decades in a Middle Eastern country. A total of 10,915 patients were admitted with initial AMI with mean age of 53 ± 11.8 years. Comparing the two decades (1991–2000) to (2001–2010), the use of antiplatelet drugs increased from 84% to 95%, β-blockers increased from 38% to 56%, and angiotensin converting enzyme inhibitors (ACEI) increased from 12% to 36% (P<0.001 for all). The rates of PCI increased from 2.5% to 14.6% and thrombolytic therapy decreased from 71% to 65% (P<0.001 for all). While the rate of hospitalization with Initial MI increased from 34% to 66%, and the average length of hospital stay decreased from 6.4 ± 3 to 4.6 ± 3, all hospital outcomes parameters improved significantly including a 39% reduction in in-hospital Mortality. Multivariate logistic regression analysis showed that higher utilization of antiplatelet drugs, β-blockers, and ACEI were the main contributors to better hospital outcomes. Over the study period, there was a significant increase in the hospitalization rate in patients presenting with initial AMI. Evidence-based medical therapies appear to be associated with a substantial improvement in outcome and in-hospital mortality. |
| format | Article |
| id | doaj-art-44d926a1d8024d7ab3bf1eaeb86205a1 |
| institution | Kabale University |
| issn | 2090-8016 2090-0597 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Cardiology Research and Practice |
| spelling | doaj-art-44d926a1d8024d7ab3bf1eaeb86205a12025-02-03T01:32:05ZengWileyCardiology Research and Practice2090-80162090-05972014-01-01201410.1155/2014/464323464323Mortality Trends in Patients Hospitalized with the Initial Acute Myocardial Infarction in a Middle Eastern Country over 20 YearsEmad Ahmed0Jassim Al Suwaidi1Ayman El-Menyar2Hajar A. H. AlBinali3Rajvir Singh4A. A. Gehani5Department of Adult Cardiology and Cardiovascular Surgery, Heart Hospital, P.O. Box 3050, Doha, QatarDepartment of Adult Cardiology and Cardiovascular Surgery, Heart Hospital, P.O. Box 3050, Doha, QatarDepartment of Clinical Medicine, Weill Cornell Medical School, P.O. Box 24144, Doha, QatarDepartment of Adult Cardiology and Cardiovascular Surgery, Heart Hospital, P.O. Box 3050, Doha, QatarDepartment of Adult Cardiology and Cardiovascular Surgery, Heart Hospital, P.O. Box 3050, Doha, QatarDepartment of Adult Cardiology and Cardiovascular Surgery, Heart Hospital, P.O. Box 3050, Doha, QatarWe aimed to define the temporal trend in the initial Acute Myocardial Infarction (AMI) management and outcome during the last two decades in a Middle Eastern country. A total of 10,915 patients were admitted with initial AMI with mean age of 53 ± 11.8 years. Comparing the two decades (1991–2000) to (2001–2010), the use of antiplatelet drugs increased from 84% to 95%, β-blockers increased from 38% to 56%, and angiotensin converting enzyme inhibitors (ACEI) increased from 12% to 36% (P<0.001 for all). The rates of PCI increased from 2.5% to 14.6% and thrombolytic therapy decreased from 71% to 65% (P<0.001 for all). While the rate of hospitalization with Initial MI increased from 34% to 66%, and the average length of hospital stay decreased from 6.4 ± 3 to 4.6 ± 3, all hospital outcomes parameters improved significantly including a 39% reduction in in-hospital Mortality. Multivariate logistic regression analysis showed that higher utilization of antiplatelet drugs, β-blockers, and ACEI were the main contributors to better hospital outcomes. Over the study period, there was a significant increase in the hospitalization rate in patients presenting with initial AMI. Evidence-based medical therapies appear to be associated with a substantial improvement in outcome and in-hospital mortality.http://dx.doi.org/10.1155/2014/464323 |
| spellingShingle | Emad Ahmed Jassim Al Suwaidi Ayman El-Menyar Hajar A. H. AlBinali Rajvir Singh A. A. Gehani Mortality Trends in Patients Hospitalized with the Initial Acute Myocardial Infarction in a Middle Eastern Country over 20 Years Cardiology Research and Practice |
| title | Mortality Trends in Patients Hospitalized with the Initial Acute Myocardial Infarction in a Middle Eastern Country over 20 Years |
| title_full | Mortality Trends in Patients Hospitalized with the Initial Acute Myocardial Infarction in a Middle Eastern Country over 20 Years |
| title_fullStr | Mortality Trends in Patients Hospitalized with the Initial Acute Myocardial Infarction in a Middle Eastern Country over 20 Years |
| title_full_unstemmed | Mortality Trends in Patients Hospitalized with the Initial Acute Myocardial Infarction in a Middle Eastern Country over 20 Years |
| title_short | Mortality Trends in Patients Hospitalized with the Initial Acute Myocardial Infarction in a Middle Eastern Country over 20 Years |
| title_sort | mortality trends in patients hospitalized with the initial acute myocardial infarction in a middle eastern country over 20 years |
| url | http://dx.doi.org/10.1155/2014/464323 |
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