Extraction, Purification, Structural Characteristics, Biological Activities, and Applications of Polysaccharides from <i>Gastrodia elata</i>: A Review
<i>Gastrodia elata</i> Blume is a well-known medicinal and edible plant in China, celebrated for its extensive history in traditional medicine and functional food applications. Among its key bioactive components, polysaccharides have drawn significant attention from researchers in the fi...
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2025-01-01
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| author | Yan Yang Yonglin Hai Yongcheng Yang Rouyuan Wen Le Wang Yan Qian Jiaxian Zhang Yongguo Li Zhilong Shi Haizhu Zhang |
| author_facet | Yan Yang Yonglin Hai Yongcheng Yang Rouyuan Wen Le Wang Yan Qian Jiaxian Zhang Yongguo Li Zhilong Shi Haizhu Zhang |
| author_sort | Yan Yang |
| collection | DOAJ |
| description | <i>Gastrodia elata</i> Blume is a well-known medicinal and edible plant in China, celebrated for its extensive history in traditional medicine and functional food applications. Among its key bioactive components, polysaccharides have drawn significant attention from researchers in the fields of health food and medicine due to their potential health benefits. Recent studies have revealed various biological activities associated with <i>G. elata</i> polysaccharides, including antioxidant, anti-tumor, anti-inflammatory, antibacterial, anti-aging, immune regulation, and neuroprotective properties. However, a comprehensive overview of these polysaccharides remains elusive. Specifically, relationship between the structure and activity of <i>G. elata</i> polysaccharides, along with the mechanisms through which various types exert their biological effects, has yet to be fully elucidated. This knowledge gap may impede the further development and utilization of <i>G. elata</i> polysaccharides in medicine, health products, food, and cosmetics. This paper provides a comprehensive overview of recent advancements in extraction, separation, purification, biological activities, and applications of <i>G. elata</i> polysaccharides. Additionally, it delves into structure-activity relationships and pharmacological mechanisms of these polysaccharides, giving support for future research to enhance their application in medicine, food, health products, and cosmetics. |
| format | Article |
| id | doaj-art-44d28474006443a8bd562f271296c29f |
| institution | Kabale University |
| issn | 1420-3049 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj-art-44d28474006443a8bd562f271296c29f2025-01-24T13:43:18ZengMDPI AGMolecules1420-30492025-01-0130226210.3390/molecules30020262Extraction, Purification, Structural Characteristics, Biological Activities, and Applications of Polysaccharides from <i>Gastrodia elata</i>: A ReviewYan Yang0Yonglin Hai1Yongcheng Yang2Rouyuan Wen3Le Wang4Yan Qian5Jiaxian Zhang6Yongguo Li7Zhilong Shi8Haizhu Zhang9College of Pharmacy, Dali University, Dali 671000, ChinaCollege of Pharmacy, Dali University, Dali 671000, ChinaCollege of Pharmacy, Dali University, Dali 671000, ChinaCollege of Pharmacy, Dali University, Dali 671000, ChinaCollege of Pharmacy, Dali University, Dali 671000, ChinaCollege of Pharmacy, Dali University, Dali 671000, ChinaCollege of Pharmacy, Dali University, Dali 671000, ChinaCollege of Pharmacy, Dali University, Dali 671000, ChinaYunnan Key Laboratory of Gastrodia and Fungi Symbiotic Biology, Zhaotong University, Zhaotong 657000, China College of Pharmacy, Dali University, Dali 671000, China<i>Gastrodia elata</i> Blume is a well-known medicinal and edible plant in China, celebrated for its extensive history in traditional medicine and functional food applications. Among its key bioactive components, polysaccharides have drawn significant attention from researchers in the fields of health food and medicine due to their potential health benefits. Recent studies have revealed various biological activities associated with <i>G. elata</i> polysaccharides, including antioxidant, anti-tumor, anti-inflammatory, antibacterial, anti-aging, immune regulation, and neuroprotective properties. However, a comprehensive overview of these polysaccharides remains elusive. Specifically, relationship between the structure and activity of <i>G. elata</i> polysaccharides, along with the mechanisms through which various types exert their biological effects, has yet to be fully elucidated. This knowledge gap may impede the further development and utilization of <i>G. elata</i> polysaccharides in medicine, health products, food, and cosmetics. This paper provides a comprehensive overview of recent advancements in extraction, separation, purification, biological activities, and applications of <i>G. elata</i> polysaccharides. Additionally, it delves into structure-activity relationships and pharmacological mechanisms of these polysaccharides, giving support for future research to enhance their application in medicine, food, health products, and cosmetics.https://www.mdpi.com/1420-3049/30/2/262<i>G. elata</i> polysaccharidesextractionpurificationstructural characterizationbiological activity |
| spellingShingle | Yan Yang Yonglin Hai Yongcheng Yang Rouyuan Wen Le Wang Yan Qian Jiaxian Zhang Yongguo Li Zhilong Shi Haizhu Zhang Extraction, Purification, Structural Characteristics, Biological Activities, and Applications of Polysaccharides from <i>Gastrodia elata</i>: A Review Molecules <i>G. elata</i> polysaccharides extraction purification structural characterization biological activity |
| title | Extraction, Purification, Structural Characteristics, Biological Activities, and Applications of Polysaccharides from <i>Gastrodia elata</i>: A Review |
| title_full | Extraction, Purification, Structural Characteristics, Biological Activities, and Applications of Polysaccharides from <i>Gastrodia elata</i>: A Review |
| title_fullStr | Extraction, Purification, Structural Characteristics, Biological Activities, and Applications of Polysaccharides from <i>Gastrodia elata</i>: A Review |
| title_full_unstemmed | Extraction, Purification, Structural Characteristics, Biological Activities, and Applications of Polysaccharides from <i>Gastrodia elata</i>: A Review |
| title_short | Extraction, Purification, Structural Characteristics, Biological Activities, and Applications of Polysaccharides from <i>Gastrodia elata</i>: A Review |
| title_sort | extraction purification structural characteristics biological activities and applications of polysaccharides from i gastrodia elata i a review |
| topic | <i>G. elata</i> polysaccharides extraction purification structural characterization biological activity |
| url | https://www.mdpi.com/1420-3049/30/2/262 |
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