Protocol to identify small-molecule inhibitors against cancer drug resistance
Summary: Drug resistance has emerged as a critical challenge in clinical cancer treatment. Here, we present a high-throughput screening protocol to identify therapeutic small-molecule inhibitors against drug-resistant cancer cells. We detail the steps for constructing drug-resistant cell models, exe...
Saved in:
Main Authors: | Juan Wei, She-Yu Zhang, Xue-Yuan Zhou, Yong Wei, Hao-Ran Jia, Qin Wu, Weihong Tan |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2025-03-01
|
Series: | STAR Protocols |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2666166725000115 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
siMacro: A Fast and Easy Data Processing Tool for Cell-Based Genomewide siRNA Screens
by: Nitin Kumar Singh, et al.
Published: (2013-03-01) -
A multiplex method for rapidly identifying viral protease inhibitors
by: Seo Jung Hong, et al.
Published: (2025-01-01) -
A Phage‐Based Approach to Identify Antivirulence Inhibitors of Bacterial Type IV Pili
by: Tori M. Shimozono, et al.
Published: (2025-01-01) -
Virtual Screening for Potential Inhibitors of NS3 Protein of Zika Virus
by: Maheswata Sahoo, et al.
Published: (2016-09-01) -
Single-cell morphological tracking of cell states to identify small-molecule modulators of liver differentiation
by: Rebecca E. Graham, et al.
Published: (2025-02-01)