Impact of electronic AKI alert/care bundle on AKI inpatient outcomes: a retrospective single-center cohort study

Background Outcomes among acute kidney injury (AKI) patients are poor in United Kingdom (UK) hospitals, and electronic alerts and care bundles may improve them. We implemented such a system at West Suffolk Hospital (WSH) called the ‘AKI order set’. We aimed to assess its impact on all-cause mortalit...

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Main Authors: Michael Chen-Xu, Christopher Kassam, Emma Cameron, Szymon Ryba, Vivian Yiu
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Renal Failure
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Online Access:https://www.tandfonline.com/doi/10.1080/0886022X.2024.2313177
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author Michael Chen-Xu
Christopher Kassam
Emma Cameron
Szymon Ryba
Vivian Yiu
author_facet Michael Chen-Xu
Christopher Kassam
Emma Cameron
Szymon Ryba
Vivian Yiu
author_sort Michael Chen-Xu
collection DOAJ
description Background Outcomes among acute kidney injury (AKI) patients are poor in United Kingdom (UK) hospitals, and electronic alerts and care bundles may improve them. We implemented such a system at West Suffolk Hospital (WSH) called the ‘AKI order set’. We aimed to assess its impact on all-cause mortality, length of stay (LOS) and renal function among AKI patients, and its utilization.Methods Retrospective, single-center cohort study of patients ≥ 18 years old with AKI at WSH, a 430-bed general hospital serving a rural UK population of approximately 280,000. 7243 unique AKI events representing 5728 patients with full data were identified automatically from our electronic health record (EHR) between 02 September 2018 and 1 July 2021 (median age 78 years, 51% male). All-cause mortality, LOS and improvement in AKI stage, demographic and comorbidity data, medications and AKI order set use were automatically collected from the EHR.Results The AKI order set was used in 9.8% of AKI events and was associated with 28% lower odds of all-cause mortality (multivariable odds ratio [OR] 0.72, 95% confidence interval [CI] 0.57–0.91). Median LOS was longer when the AKI order set was utilized than when not (11.8 versus 8.8 days, p < .001), but was independently associated with improvement in the AKI stage (28.9% versus 8.7%, p < .001; univariable OR 4.25, 95% CI 3.53–5.10, multivariable OR 4.27, 95% CI 3.54–5.14).Conclusions AKI order set use led to improvements in all-cause mortality and renal function, but longer LOS, among AKI patients at WSH.
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spelling doaj-art-44b09f43ac7842c8b350eccbe977a5692025-01-23T04:17:48ZengTaylor & Francis GroupRenal Failure0886-022X1525-60492024-12-0146110.1080/0886022X.2024.2313177Impact of electronic AKI alert/care bundle on AKI inpatient outcomes: a retrospective single-center cohort studyMichael Chen-Xu0Christopher Kassam1Emma Cameron2Szymon Ryba3Vivian Yiu4West Suffolk Hospital NHS Foundation Trust, Suffolk, UKWest Suffolk Hospital NHS Foundation Trust, Suffolk, UKWest Suffolk Hospital NHS Foundation Trust, Suffolk, UKWest Suffolk Hospital NHS Foundation Trust, Suffolk, UKWest Suffolk Hospital NHS Foundation Trust, Suffolk, UKBackground Outcomes among acute kidney injury (AKI) patients are poor in United Kingdom (UK) hospitals, and electronic alerts and care bundles may improve them. We implemented such a system at West Suffolk Hospital (WSH) called the ‘AKI order set’. We aimed to assess its impact on all-cause mortality, length of stay (LOS) and renal function among AKI patients, and its utilization.Methods Retrospective, single-center cohort study of patients ≥ 18 years old with AKI at WSH, a 430-bed general hospital serving a rural UK population of approximately 280,000. 7243 unique AKI events representing 5728 patients with full data were identified automatically from our electronic health record (EHR) between 02 September 2018 and 1 July 2021 (median age 78 years, 51% male). All-cause mortality, LOS and improvement in AKI stage, demographic and comorbidity data, medications and AKI order set use were automatically collected from the EHR.Results The AKI order set was used in 9.8% of AKI events and was associated with 28% lower odds of all-cause mortality (multivariable odds ratio [OR] 0.72, 95% confidence interval [CI] 0.57–0.91). Median LOS was longer when the AKI order set was utilized than when not (11.8 versus 8.8 days, p < .001), but was independently associated with improvement in the AKI stage (28.9% versus 8.7%, p < .001; univariable OR 4.25, 95% CI 3.53–5.10, multivariable OR 4.27, 95% CI 3.54–5.14).Conclusions AKI order set use led to improvements in all-cause mortality and renal function, but longer LOS, among AKI patients at WSH.https://www.tandfonline.com/doi/10.1080/0886022X.2024.2313177Acute kidney injuryelectronic alertingcare bundlerenal failurequality improvement
spellingShingle Michael Chen-Xu
Christopher Kassam
Emma Cameron
Szymon Ryba
Vivian Yiu
Impact of electronic AKI alert/care bundle on AKI inpatient outcomes: a retrospective single-center cohort study
Renal Failure
Acute kidney injury
electronic alerting
care bundle
renal failure
quality improvement
title Impact of electronic AKI alert/care bundle on AKI inpatient outcomes: a retrospective single-center cohort study
title_full Impact of electronic AKI alert/care bundle on AKI inpatient outcomes: a retrospective single-center cohort study
title_fullStr Impact of electronic AKI alert/care bundle on AKI inpatient outcomes: a retrospective single-center cohort study
title_full_unstemmed Impact of electronic AKI alert/care bundle on AKI inpatient outcomes: a retrospective single-center cohort study
title_short Impact of electronic AKI alert/care bundle on AKI inpatient outcomes: a retrospective single-center cohort study
title_sort impact of electronic aki alert care bundle on aki inpatient outcomes a retrospective single center cohort study
topic Acute kidney injury
electronic alerting
care bundle
renal failure
quality improvement
url https://www.tandfonline.com/doi/10.1080/0886022X.2024.2313177
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