Complex Brain Network Analysis and Its Applications to Brain Disorders: A Survey

It is well known that most brain disorders are complex diseases, such as Alzheimer’s disease (AD) and schizophrenia (SCZ). In general, brain regions and their interactions can be modeled as complex brain network, which describe highly efficient information transmission in a brain. Therefore, complex...

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Main Authors: Jin Liu, Min Li, Yi Pan, Wei Lan, Ruiqing Zheng, Fang-Xiang Wu, Jianxin Wang
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Complexity
Online Access:http://dx.doi.org/10.1155/2017/8362741
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author Jin Liu
Min Li
Yi Pan
Wei Lan
Ruiqing Zheng
Fang-Xiang Wu
Jianxin Wang
author_facet Jin Liu
Min Li
Yi Pan
Wei Lan
Ruiqing Zheng
Fang-Xiang Wu
Jianxin Wang
author_sort Jin Liu
collection DOAJ
description It is well known that most brain disorders are complex diseases, such as Alzheimer’s disease (AD) and schizophrenia (SCZ). In general, brain regions and their interactions can be modeled as complex brain network, which describe highly efficient information transmission in a brain. Therefore, complex brain network analysis plays an important role in the study of complex brain diseases. With the development of noninvasive neuroimaging and electrophysiological techniques, experimental data can be produced for constructing complex brain networks. In recent years, researchers have found that brain networks constructed by using neuroimaging data and electrophysiological data have many important topological properties, such as small-world property, modularity, and rich club. More importantly, many brain disorders have been found to be associated with the abnormal topological structures of brain networks. These findings provide not only a new perspective to explore the pathological mechanisms of brain disorders, but also guidance for early diagnosis and treatment of brain disorders. The purpose of this survey is to provide a comprehensive overview for complex brain network analysis and its applications to brain disorders.
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spelling doaj-art-44a3ecd8cdf145c6be6572c8724172dd2025-02-03T00:59:55ZengWileyComplexity1076-27871099-05262017-01-01201710.1155/2017/83627418362741Complex Brain Network Analysis and Its Applications to Brain Disorders: A SurveyJin Liu0Min Li1Yi Pan2Wei Lan3Ruiqing Zheng4Fang-Xiang Wu5Jianxin Wang6School of Information Science and Engineering, Central South University, Changsha 410083, ChinaSchool of Information Science and Engineering, Central South University, Changsha 410083, ChinaDepartment of Computer Science, Georgia State University, Atlanta, GA 30302, USASchool of Information Science and Engineering, Central South University, Changsha 410083, ChinaSchool of Information Science and Engineering, Central South University, Changsha 410083, ChinaDivision of Biomedical Engineering and Department of Mechanical Engineering, University of Saskatchewan, Saskatoon, SK, S7N5A9, CanadaSchool of Information Science and Engineering, Central South University, Changsha 410083, ChinaIt is well known that most brain disorders are complex diseases, such as Alzheimer’s disease (AD) and schizophrenia (SCZ). In general, brain regions and their interactions can be modeled as complex brain network, which describe highly efficient information transmission in a brain. Therefore, complex brain network analysis plays an important role in the study of complex brain diseases. With the development of noninvasive neuroimaging and electrophysiological techniques, experimental data can be produced for constructing complex brain networks. In recent years, researchers have found that brain networks constructed by using neuroimaging data and electrophysiological data have many important topological properties, such as small-world property, modularity, and rich club. More importantly, many brain disorders have been found to be associated with the abnormal topological structures of brain networks. These findings provide not only a new perspective to explore the pathological mechanisms of brain disorders, but also guidance for early diagnosis and treatment of brain disorders. The purpose of this survey is to provide a comprehensive overview for complex brain network analysis and its applications to brain disorders.http://dx.doi.org/10.1155/2017/8362741
spellingShingle Jin Liu
Min Li
Yi Pan
Wei Lan
Ruiqing Zheng
Fang-Xiang Wu
Jianxin Wang
Complex Brain Network Analysis and Its Applications to Brain Disorders: A Survey
Complexity
title Complex Brain Network Analysis and Its Applications to Brain Disorders: A Survey
title_full Complex Brain Network Analysis and Its Applications to Brain Disorders: A Survey
title_fullStr Complex Brain Network Analysis and Its Applications to Brain Disorders: A Survey
title_full_unstemmed Complex Brain Network Analysis and Its Applications to Brain Disorders: A Survey
title_short Complex Brain Network Analysis and Its Applications to Brain Disorders: A Survey
title_sort complex brain network analysis and its applications to brain disorders a survey
url http://dx.doi.org/10.1155/2017/8362741
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