Role of the AP2 beta-appendage hub in recruiting partners for clathrin-coated vesicle assembly.

Adaptor protein complex 2 alpha and beta-appendage domains act as hubs for the assembly of accessory protein networks involved in clathrin-coated vesicle formation. We identify a large repertoire of beta-appendage interactors by mass spectrometry. These interact with two distinct ligand interaction...

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Bibliographic Details
Main Authors: Eva M Schmid, Marijn G J Ford, Anne Burtey, Gerrit J K Praefcke, Sew-Yeu Peak-Chew, Ian G Mills, Alexandre Benmerah, Harvey T McMahon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-09-01
Series:PLoS Biology
Online Access:https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.0040262&type=printable
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