Evaluation of Hematological Parameters in Partial Exchange and Packed Cell Transfusion in Treatment of Severe Anemia in Pregnancy
Objectives. Anemia is a major public health problem throughout the world which assumes prominence in pregnant mothers. Patients with severe anemia continue to present themselves at term or in labor. This study was conducted to compare the improvements in hematological parameters of patients receivin...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Anemia |
| Online Access: | http://dx.doi.org/10.1155/2012/608658 |
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| author | Sudha Salhan Vrijesh Tripathi Rajvir Singh Harsha S. Gaikwad |
| author_facet | Sudha Salhan Vrijesh Tripathi Rajvir Singh Harsha S. Gaikwad |
| author_sort | Sudha Salhan |
| collection | DOAJ |
| description | Objectives. Anemia is a major public health problem throughout the world which assumes prominence in pregnant mothers. Patients with severe anemia continue to present themselves at term or in labor. This study was conducted to compare the improvements in hematological parameters of patients receiving partial exchange blood transfusion and transfusion of packed cells without exchange. Methods. One hundred and twenty-five severely anemic antenatal mothers were admitted from outpatient service. Partial exchange transfusion was given to sixty-six patients while fifty-nine received transfusion of packed cells with frusemide cover. Results. The two groups were comparable in terms of age, height, weight, religion, diet, education, occupation of self and husband, and income. Hemoglobin level in Group 1 was comparatively less than Group 2 at prelevel (5.2±1.5 versus 6.6±2.3, P=0.001) and postlevel (7.2±1.5 versus 8.6±1.8, P=0.001), respectively, but there was no significant difference between the two modes of transfusion (2.09±1.6 versus 2.01±1.5, P=0.78). Conclusion. The study produced an equally significant improvement in hematological parameters in partial exchange and packed cell transfusion. Platelet counts were significantly less in partial exchange as compared with packed cell transfusion. |
| format | Article |
| id | doaj-art-445afbee3d2e4c23a6bf35c329a7a1d3 |
| institution | Kabale University |
| issn | 2090-1267 2090-1275 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Anemia |
| spelling | doaj-art-445afbee3d2e4c23a6bf35c329a7a1d32025-02-03T05:46:56ZengWileyAnemia2090-12672090-12752012-01-01201210.1155/2012/608658608658Evaluation of Hematological Parameters in Partial Exchange and Packed Cell Transfusion in Treatment of Severe Anemia in PregnancySudha Salhan0Vrijesh Tripathi1Rajvir Singh2Harsha S. Gaikwad3Department of Obstetrics & Gynecology, Hamdard Institute of Medical Sciences & Research, New Delhi 110062, IndiaThe Department of Mathematics & Statistics, The University of the West Indies, St. Augustine Campus, Trinidad and TobagoMedical Research Centre and Cardiology, CCS Department, Hamad Medical Corporation (HMC), Doha, QatarDepartment of Obstetrics & Gynecology, Vardhman Mahavir Medical College & Safdarjung Hospital, New Delhi 110029, IndiaObjectives. Anemia is a major public health problem throughout the world which assumes prominence in pregnant mothers. Patients with severe anemia continue to present themselves at term or in labor. This study was conducted to compare the improvements in hematological parameters of patients receiving partial exchange blood transfusion and transfusion of packed cells without exchange. Methods. One hundred and twenty-five severely anemic antenatal mothers were admitted from outpatient service. Partial exchange transfusion was given to sixty-six patients while fifty-nine received transfusion of packed cells with frusemide cover. Results. The two groups were comparable in terms of age, height, weight, religion, diet, education, occupation of self and husband, and income. Hemoglobin level in Group 1 was comparatively less than Group 2 at prelevel (5.2±1.5 versus 6.6±2.3, P=0.001) and postlevel (7.2±1.5 versus 8.6±1.8, P=0.001), respectively, but there was no significant difference between the two modes of transfusion (2.09±1.6 versus 2.01±1.5, P=0.78). Conclusion. The study produced an equally significant improvement in hematological parameters in partial exchange and packed cell transfusion. Platelet counts were significantly less in partial exchange as compared with packed cell transfusion.http://dx.doi.org/10.1155/2012/608658 |
| spellingShingle | Sudha Salhan Vrijesh Tripathi Rajvir Singh Harsha S. Gaikwad Evaluation of Hematological Parameters in Partial Exchange and Packed Cell Transfusion in Treatment of Severe Anemia in Pregnancy Anemia |
| title | Evaluation of Hematological Parameters in Partial Exchange and Packed Cell Transfusion in Treatment of Severe Anemia in Pregnancy |
| title_full | Evaluation of Hematological Parameters in Partial Exchange and Packed Cell Transfusion in Treatment of Severe Anemia in Pregnancy |
| title_fullStr | Evaluation of Hematological Parameters in Partial Exchange and Packed Cell Transfusion in Treatment of Severe Anemia in Pregnancy |
| title_full_unstemmed | Evaluation of Hematological Parameters in Partial Exchange and Packed Cell Transfusion in Treatment of Severe Anemia in Pregnancy |
| title_short | Evaluation of Hematological Parameters in Partial Exchange and Packed Cell Transfusion in Treatment of Severe Anemia in Pregnancy |
| title_sort | evaluation of hematological parameters in partial exchange and packed cell transfusion in treatment of severe anemia in pregnancy |
| url | http://dx.doi.org/10.1155/2012/608658 |
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