Deformable Image Registration with Inclusion of Autodetected Homologous Tissue Features

A novel deformable registration algorithm is proposed in the application of radiation therapy. The algorithm starts with autodetection of a number of points with distinct tissue features. The feature points are then matched by using the scale invariance features transform (SIFT) method. The associat...

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Main Authors: Qingsong Zhu, Jia Gu, Yaoqin Xie
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1100/2012/913693
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author Qingsong Zhu
Jia Gu
Yaoqin Xie
author_facet Qingsong Zhu
Jia Gu
Yaoqin Xie
author_sort Qingsong Zhu
collection DOAJ
description A novel deformable registration algorithm is proposed in the application of radiation therapy. The algorithm starts with autodetection of a number of points with distinct tissue features. The feature points are then matched by using the scale invariance features transform (SIFT) method. The associated feature point pairs are served as landmarks for the subsequent thin plate spline (TPS) interpolation. Several registration experiments using both digital phantom and clinical data demonstrate the accuracy and efficiency of the method. For the 3D phantom case, markers with error less than 2 mm are over 85% of total test markers, and it takes only 2-3 minutes for 3D feature points association. The proposed method provides a clinically practical solution and should be valuable for various image-guided radiation therapy (IGRT) applications.
format Article
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institution Kabale University
issn 1537-744X
language English
publishDate 2012-01-01
publisher Wiley
record_format Article
series The Scientific World Journal
spelling doaj-art-44535495d4004e56a47307f783c54f722025-02-03T01:31:25ZengWileyThe Scientific World Journal1537-744X2012-01-01201210.1100/2012/913693913693Deformable Image Registration with Inclusion of Autodetected Homologous Tissue FeaturesQingsong Zhu0Jia Gu1Yaoqin Xie2Key Laboratory for Health Informatics, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, ChinaKey Laboratory for Health Informatics, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, ChinaKey Laboratory for Health Informatics, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, ChinaA novel deformable registration algorithm is proposed in the application of radiation therapy. The algorithm starts with autodetection of a number of points with distinct tissue features. The feature points are then matched by using the scale invariance features transform (SIFT) method. The associated feature point pairs are served as landmarks for the subsequent thin plate spline (TPS) interpolation. Several registration experiments using both digital phantom and clinical data demonstrate the accuracy and efficiency of the method. For the 3D phantom case, markers with error less than 2 mm are over 85% of total test markers, and it takes only 2-3 minutes for 3D feature points association. The proposed method provides a clinically practical solution and should be valuable for various image-guided radiation therapy (IGRT) applications.http://dx.doi.org/10.1100/2012/913693
spellingShingle Qingsong Zhu
Jia Gu
Yaoqin Xie
Deformable Image Registration with Inclusion of Autodetected Homologous Tissue Features
The Scientific World Journal
title Deformable Image Registration with Inclusion of Autodetected Homologous Tissue Features
title_full Deformable Image Registration with Inclusion of Autodetected Homologous Tissue Features
title_fullStr Deformable Image Registration with Inclusion of Autodetected Homologous Tissue Features
title_full_unstemmed Deformable Image Registration with Inclusion of Autodetected Homologous Tissue Features
title_short Deformable Image Registration with Inclusion of Autodetected Homologous Tissue Features
title_sort deformable image registration with inclusion of autodetected homologous tissue features
url http://dx.doi.org/10.1100/2012/913693
work_keys_str_mv AT qingsongzhu deformableimageregistrationwithinclusionofautodetectedhomologoustissuefeatures
AT jiagu deformableimageregistrationwithinclusionofautodetectedhomologoustissuefeatures
AT yaoqinxie deformableimageregistrationwithinclusionofautodetectedhomologoustissuefeatures