Electrocatalytic Study of Paracetamol at a Single-Walled Carbon Nanotube/Nickel Nanocomposite Modified Glassy Carbon Electrode
A rapid, simple, and sensitive method for the electrochemical determination of paracetamol was developed. A single-walled carbon nanotube/nickel (SWCNT/Ni) nanocomposite was prepared and immobilized on a glassy carbon electrode (GCE) surface via mechanical attachment. This paper reports the voltamme...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2015-01-01
|
| Series: | Advances in Materials Science and Engineering |
| Online Access: | http://dx.doi.org/10.1155/2015/742548 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832562942050041856 |
|---|---|
| author | Koh Sing Ngai Wee Tee Tan Zulkarnain Zainal Ruzniza Mohd Zawawi Joon Ching Juan |
| author_facet | Koh Sing Ngai Wee Tee Tan Zulkarnain Zainal Ruzniza Mohd Zawawi Joon Ching Juan |
| author_sort | Koh Sing Ngai |
| collection | DOAJ |
| description | A rapid, simple, and sensitive method for the electrochemical determination of paracetamol was developed. A single-walled carbon nanotube/nickel (SWCNT/Ni) nanocomposite was prepared and immobilized on a glassy carbon electrode (GCE) surface via mechanical attachment. This paper reports the voltammetry study on the effect of paracetamol concentration, scan rate, pH, and temperature at a SWCNT/Ni-modified electrode in the determination of paracetamol. The characterization of the SWCNT/Ni/GCE was performed by cyclic voltammetry. Variable pressure scanning electron microscopy (VPSEM) and energy dispersive X-ray (EDX) spectrometer were used to examine the surface morphology and elemental profile of the modified electrode, respectively. Cyclic voltammetry showed significant enhancement in peak current for the determination of paracetamol at the SWCNT/Ni-modified electrode. A linear calibration curve was obtained for the paracetamol concentration between 0.05 and 0.50 mM. The SWCNT/Ni/GCE displayed a sensitivity of 64 mA M−1 and a detection limit of 1.17 × 10−7 M in paracetamol detection. The proposed electrode can be applied for the determination of paracetamol in real pharmaceutical samples with satisfactory performance. Results indicate that electrodes modified with SWCNT and nickel nanoparticles exhibit better electrocatalytic activity towards paracetamol. |
| format | Article |
| id | doaj-art-442152ffe536480f931f76f4994f499f |
| institution | Kabale University |
| issn | 1687-8434 1687-8442 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Advances in Materials Science and Engineering |
| spelling | doaj-art-442152ffe536480f931f76f4994f499f2025-02-03T01:21:18ZengWileyAdvances in Materials Science and Engineering1687-84341687-84422015-01-01201510.1155/2015/742548742548Electrocatalytic Study of Paracetamol at a Single-Walled Carbon Nanotube/Nickel Nanocomposite Modified Glassy Carbon ElectrodeKoh Sing Ngai0Wee Tee Tan1Zulkarnain Zainal2Ruzniza Mohd Zawawi3Joon Ching Juan4Department of Chemistry, Faculty of Science, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, MalaysiaDepartment of Chemistry, Faculty of Science, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, MalaysiaDepartment of Chemistry, Faculty of Science, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, MalaysiaDepartment of Chemistry, Faculty of Science, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, MalaysiaNanotechnology & Catalysis Research Centre (NANOCAT), University of Malaya, 50603 Kuala Lumpur, MalaysiaA rapid, simple, and sensitive method for the electrochemical determination of paracetamol was developed. A single-walled carbon nanotube/nickel (SWCNT/Ni) nanocomposite was prepared and immobilized on a glassy carbon electrode (GCE) surface via mechanical attachment. This paper reports the voltammetry study on the effect of paracetamol concentration, scan rate, pH, and temperature at a SWCNT/Ni-modified electrode in the determination of paracetamol. The characterization of the SWCNT/Ni/GCE was performed by cyclic voltammetry. Variable pressure scanning electron microscopy (VPSEM) and energy dispersive X-ray (EDX) spectrometer were used to examine the surface morphology and elemental profile of the modified electrode, respectively. Cyclic voltammetry showed significant enhancement in peak current for the determination of paracetamol at the SWCNT/Ni-modified electrode. A linear calibration curve was obtained for the paracetamol concentration between 0.05 and 0.50 mM. The SWCNT/Ni/GCE displayed a sensitivity of 64 mA M−1 and a detection limit of 1.17 × 10−7 M in paracetamol detection. The proposed electrode can be applied for the determination of paracetamol in real pharmaceutical samples with satisfactory performance. Results indicate that electrodes modified with SWCNT and nickel nanoparticles exhibit better electrocatalytic activity towards paracetamol.http://dx.doi.org/10.1155/2015/742548 |
| spellingShingle | Koh Sing Ngai Wee Tee Tan Zulkarnain Zainal Ruzniza Mohd Zawawi Joon Ching Juan Electrocatalytic Study of Paracetamol at a Single-Walled Carbon Nanotube/Nickel Nanocomposite Modified Glassy Carbon Electrode Advances in Materials Science and Engineering |
| title | Electrocatalytic Study of Paracetamol at a Single-Walled Carbon Nanotube/Nickel Nanocomposite Modified Glassy Carbon Electrode |
| title_full | Electrocatalytic Study of Paracetamol at a Single-Walled Carbon Nanotube/Nickel Nanocomposite Modified Glassy Carbon Electrode |
| title_fullStr | Electrocatalytic Study of Paracetamol at a Single-Walled Carbon Nanotube/Nickel Nanocomposite Modified Glassy Carbon Electrode |
| title_full_unstemmed | Electrocatalytic Study of Paracetamol at a Single-Walled Carbon Nanotube/Nickel Nanocomposite Modified Glassy Carbon Electrode |
| title_short | Electrocatalytic Study of Paracetamol at a Single-Walled Carbon Nanotube/Nickel Nanocomposite Modified Glassy Carbon Electrode |
| title_sort | electrocatalytic study of paracetamol at a single walled carbon nanotube nickel nanocomposite modified glassy carbon electrode |
| url | http://dx.doi.org/10.1155/2015/742548 |
| work_keys_str_mv | AT kohsingngai electrocatalyticstudyofparacetamolatasinglewalledcarbonnanotubenickelnanocompositemodifiedglassycarbonelectrode AT weeteetan electrocatalyticstudyofparacetamolatasinglewalledcarbonnanotubenickelnanocompositemodifiedglassycarbonelectrode AT zulkarnainzainal electrocatalyticstudyofparacetamolatasinglewalledcarbonnanotubenickelnanocompositemodifiedglassycarbonelectrode AT ruznizamohdzawawi electrocatalyticstudyofparacetamolatasinglewalledcarbonnanotubenickelnanocompositemodifiedglassycarbonelectrode AT joonchingjuan electrocatalyticstudyofparacetamolatasinglewalledcarbonnanotubenickelnanocompositemodifiedglassycarbonelectrode |