Abnormalities in Glutamate Metabolism and Excitotoxicity in the Retinal Diseases

In the physiological condition, glutamate acts as an excitatory neurotransmitter in the retina. However, excessive glutamate can be toxic to retinal neurons by overstimulation of the glutamate receptors. Glutamate excess is primarily attributed to perturbation in the homeostasis of the glutamate met...

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Bibliographic Details
Main Author: Makoto Ishikawa
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Scientifica
Online Access:http://dx.doi.org/10.1155/2013/528940
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