A Case of Disseminated Hypopigmented Keratoses Improved with Oral Acitretin
Disseminated hypopigmented keratosis is a distinct clinical entity and only few cases have been reported so far. Here, we present a 21-year-old man with almost 10-year history of hypopigmented, nonfollicular, keratotic lichenoid papules occurring on the extensor surfaces of the extremities, back and...
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | Case Reports in Dermatological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2017/1617375 |
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| author | Ali Haydar Eskiocak Cumhur İbrahim Bassorgun Sarp Uzun Soner Uzun |
| author_facet | Ali Haydar Eskiocak Cumhur İbrahim Bassorgun Sarp Uzun Soner Uzun |
| author_sort | Ali Haydar Eskiocak |
| collection | DOAJ |
| description | Disseminated hypopigmented keratosis is a distinct clinical entity and only few cases have been reported so far. Here, we present a 21-year-old man with almost 10-year history of hypopigmented, nonfollicular, keratotic lichenoid papules occurring on the extensor surfaces of the extremities, back and lumber region. Histopathological examination showed orthohyperkeratosis, irregular acanthosis, and sporadic papillomatosis with a normal amount of melanin and number of melanocytes. In addition, no marked inflammation or melanophages were seen. In order to exclude other possible causes, we performed laboratory tests and radiological examination which were all found to be normal. As the clinical and histopathological features of our patient were taken into account, it was considered to be compatible with the diagnosis of disseminated hypopigmented keratoses. So far, only topical therapies have been used with failure in the previously reported cases except one patient. Considering the extensive lesions, we treated the present patient with 5% salicylic acid in addition to oral acitretin and significant regression in all lesions was achieved, particularly on the keratosis. |
| format | Article |
| id | doaj-art-43d2ea52d9ac4313b0c71f1b6b04ea7b |
| institution | Kabale University |
| issn | 2090-6463 2090-6471 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Dermatological Medicine |
| spelling | doaj-art-43d2ea52d9ac4313b0c71f1b6b04ea7b2025-02-03T01:22:29ZengWileyCase Reports in Dermatological Medicine2090-64632090-64712017-01-01201710.1155/2017/16173751617375A Case of Disseminated Hypopigmented Keratoses Improved with Oral AcitretinAli Haydar Eskiocak0Cumhur İbrahim Bassorgun1Sarp Uzun2Soner Uzun3Department of Dermatology and Venereology, Akdeniz University School of Medicine Hospital, Antalya, TurkeyDepartment of Pathology, Akdeniz University School of Medicine Hospital, Antalya, TurkeyHacettepe University School of Medicine, Ankara, TurkeyDepartment of Dermatology and Venereology, Akdeniz University School of Medicine Hospital, Antalya, TurkeyDisseminated hypopigmented keratosis is a distinct clinical entity and only few cases have been reported so far. Here, we present a 21-year-old man with almost 10-year history of hypopigmented, nonfollicular, keratotic lichenoid papules occurring on the extensor surfaces of the extremities, back and lumber region. Histopathological examination showed orthohyperkeratosis, irregular acanthosis, and sporadic papillomatosis with a normal amount of melanin and number of melanocytes. In addition, no marked inflammation or melanophages were seen. In order to exclude other possible causes, we performed laboratory tests and radiological examination which were all found to be normal. As the clinical and histopathological features of our patient were taken into account, it was considered to be compatible with the diagnosis of disseminated hypopigmented keratoses. So far, only topical therapies have been used with failure in the previously reported cases except one patient. Considering the extensive lesions, we treated the present patient with 5% salicylic acid in addition to oral acitretin and significant regression in all lesions was achieved, particularly on the keratosis.http://dx.doi.org/10.1155/2017/1617375 |
| spellingShingle | Ali Haydar Eskiocak Cumhur İbrahim Bassorgun Sarp Uzun Soner Uzun A Case of Disseminated Hypopigmented Keratoses Improved with Oral Acitretin Case Reports in Dermatological Medicine |
| title | A Case of Disseminated Hypopigmented Keratoses Improved with Oral Acitretin |
| title_full | A Case of Disseminated Hypopigmented Keratoses Improved with Oral Acitretin |
| title_fullStr | A Case of Disseminated Hypopigmented Keratoses Improved with Oral Acitretin |
| title_full_unstemmed | A Case of Disseminated Hypopigmented Keratoses Improved with Oral Acitretin |
| title_short | A Case of Disseminated Hypopigmented Keratoses Improved with Oral Acitretin |
| title_sort | case of disseminated hypopigmented keratoses improved with oral acitretin |
| url | http://dx.doi.org/10.1155/2017/1617375 |
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