Current Concepts of Fracture-Related Infection

Currently, fracture-related infection (FRI) still represents great challenges in front of orthopaedic surgeons, despite great advances that have been achieved regarding its diagnosis and treatment. Although both FRI and prosthetic joint infection (PJI) belong to osteoarticular infections and share s...

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Main Authors: Si-ying He, Bin Yu, Nan Jiang
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:International Journal of Clinical Practice
Online Access:http://dx.doi.org/10.1155/2023/4839701
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author Si-ying He
Bin Yu
Nan Jiang
author_facet Si-ying He
Bin Yu
Nan Jiang
author_sort Si-ying He
collection DOAJ
description Currently, fracture-related infection (FRI) still represents great challenges in front of orthopaedic surgeons, despite great advances that have been achieved regarding its diagnosis and treatment. Although both FRI and prosthetic joint infection (PJI) belong to osteoarticular infections and share similarities, FRI displays unique characteristics. Diagnosis of FRI is sometimes difficult owing to the nonspecific symptoms, and treatment is usually tricky, with a high risk of infection recurrence. In addition, the long disease course is associated with a significantly elevated risk of disability, both physically and psychologically. Moreover, such a disorder still poses heavy economic burdens to the patients, both personally and socially. Therefore, early diagnosis and reasonable treatment are the key issues for increasing the cure rate, decreasing the risks of infection relapse and disability, and improving the life quality and prognosis of the patients. In this review, we summarized the present concepts regarding the definition, epidemiology, diagnosis, and treatment of FRI.
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series International Journal of Clinical Practice
spelling doaj-art-43c723a832594a1398bed15f9d0545a12025-02-03T06:42:44ZengWileyInternational Journal of Clinical Practice1742-12412023-01-01202310.1155/2023/4839701Current Concepts of Fracture-Related InfectionSi-ying He0Bin Yu1Nan Jiang2Division of Orthopaedics and TraumatologyDivision of Orthopaedics and TraumatologyDivision of Orthopaedics and TraumatologyCurrently, fracture-related infection (FRI) still represents great challenges in front of orthopaedic surgeons, despite great advances that have been achieved regarding its diagnosis and treatment. Although both FRI and prosthetic joint infection (PJI) belong to osteoarticular infections and share similarities, FRI displays unique characteristics. Diagnosis of FRI is sometimes difficult owing to the nonspecific symptoms, and treatment is usually tricky, with a high risk of infection recurrence. In addition, the long disease course is associated with a significantly elevated risk of disability, both physically and psychologically. Moreover, such a disorder still poses heavy economic burdens to the patients, both personally and socially. Therefore, early diagnosis and reasonable treatment are the key issues for increasing the cure rate, decreasing the risks of infection relapse and disability, and improving the life quality and prognosis of the patients. In this review, we summarized the present concepts regarding the definition, epidemiology, diagnosis, and treatment of FRI.http://dx.doi.org/10.1155/2023/4839701
spellingShingle Si-ying He
Bin Yu
Nan Jiang
Current Concepts of Fracture-Related Infection
International Journal of Clinical Practice
title Current Concepts of Fracture-Related Infection
title_full Current Concepts of Fracture-Related Infection
title_fullStr Current Concepts of Fracture-Related Infection
title_full_unstemmed Current Concepts of Fracture-Related Infection
title_short Current Concepts of Fracture-Related Infection
title_sort current concepts of fracture related infection
url http://dx.doi.org/10.1155/2023/4839701
work_keys_str_mv AT siyinghe currentconceptsoffracturerelatedinfection
AT binyu currentconceptsoffracturerelatedinfection
AT nanjiang currentconceptsoffracturerelatedinfection