Efficacy of High-Dose and Low-Dose Simvastatin on Vascular Oxidative Stress and Neurological Outcomes in Patient with Acute Ischemic Stroke: A Randomized, Double-Blind, Parallel, Controlled Trial

Backgrounds. Stroke is the leading cause of death and long-term disability. Oxidative stress is elevated during occurrence of acute ischemic stroke (AIS). Soluble LOX-1 (sLOX-1) and NO are used as biomarkers for vascular oxidative stress that can reflect stabilization of atherosclerotic plaque. Prev...

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Bibliographic Details
Main Authors: Nattaphol Uransilp, Pannawat Chaiyawatthanananthn, Sombat Muengtaweepongsa
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Neurology Research International
Online Access:http://dx.doi.org/10.1155/2018/7268924
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