Metabolomics and transcriptomics profiling of three Paris species with varied polyphyllin compositions

Abstract Most of the species in Paris have important medicinal values in China. Polyphyllins are the key components in Paris, with varying levels and compositions among different species. This study investigated polyphyllin compositions of 206 Paris samples from 16 different producing areas. 9 Paris...

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Main Authors: Ping Xu, Jia Chen, Qi Mi, Wenchun Li, You Lu, Wenxiu Luo, Mengwen Yu, Xuan Zhang, Zhenhua Tu, Honggao Xu, Guowei Zheng
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Scientific Data
Online Access:https://doi.org/10.1038/s41597-024-04066-6
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Summary:Abstract Most of the species in Paris have important medicinal values in China. Polyphyllins are the key components in Paris, with varying levels and compositions among different species. This study investigated polyphyllin compositions of 206 Paris samples from 16 different producing areas. 9 Paris polyphylla var. yunnanensis, 3 Paris fargesii, and 3 Paris forrestii were selected based on polyphyllin levels and composition for metabolome and transcriptome analysis. A total of 1,243 metabolites were identified among these samples, along with 92.11 Gb of full-length transcriptome data. This study provides potential candidate genes involved in polyphyllins synthesis in Paris, aiming to facilitate the biosynthesis of different polyphyllins.
ISSN:2052-4463