WEAKLY POSITIVE RH FACTOR, DIAGNOSED FOR THE FIRST TIME IN A WOMAN DURING PREGNANCY (CLINICAL CASE)
The weakly positive Rh factor (Du phenotype) was described by physician and researcher Frederick Stratton in 1946 as a new variant of the antigen that reacts weakly with anti-D identifying sera. It is characterized by quantitative rather than qualitative differences, unlike the partial variant: with...
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The Publishing House Medicine and Enlightenment
2024-11-01
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Series: | Мать и дитя в Кузбассе |
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Online Access: | https://mednauki.ru/index.php/MD/article/view/1149 |
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author | Юлия Сергеевна Фролова Екатерина Владимировна Грищенко Светлана Ивановна Елгина Елена Владимировна Рудаева Кира Борисовна Мозес |
author_facet | Юлия Сергеевна Фролова Екатерина Владимировна Грищенко Светлана Ивановна Елгина Елена Владимировна Рудаева Кира Борисовна Мозес |
author_sort | Юлия Сергеевна Фролова |
collection | DOAJ |
description | The weakly positive Rh factor (Du phenotype) was described by physician and researcher Frederick Stratton in 1946 as a new variant of the antigen that reacts weakly with anti-D identifying sera. It is characterized by quantitative rather than qualitative differences, unlike the partial variant: with this type of Rh affiliation, the number of antigens on the erythrocyte is reduced. In most cases, this is due to genetic reasons. About 1 % of people have a weakly positive variant of the antigen D of the Rh factor – D weak, aka, «Du». More recently, such a phenotype was defined as negative. With conventional methods for determining Rh affiliation, it was previously difficult to identify a «weak» antigen. But with the use of new immunogenetic methods, it is not difficult to determine the presence of «weakly positive» Rh.
The presented article describes a clinical case of pregnancy and childbirth in a woman with a weakly positive Rh factor. |
format | Article |
id | doaj-art-435a744b22de41bfae21cd57398fbe30 |
institution | Kabale University |
issn | 1991-010X 2542-0968 |
language | Russian |
publishDate | 2024-11-01 |
publisher | The Publishing House Medicine and Enlightenment |
record_format | Article |
series | Мать и дитя в Кузбассе |
spelling | doaj-art-435a744b22de41bfae21cd57398fbe302025-02-03T15:55:08ZrusThe Publishing House Medicine and EnlightenmentМать и дитя в Кузбассе1991-010X2542-09682024-11-012548285985WEAKLY POSITIVE RH FACTOR, DIAGNOSED FOR THE FIRST TIME IN A WOMAN DURING PREGNANCY (CLINICAL CASE)Юлия Сергеевна Фролова0Екатерина Владимировна Грищенко1Светлана Ивановна Елгина2Елена Владимировна Рудаева3Кира Борисовна Мозес4ГАУЗ КГКБ № 4, г. КемеровоГАУЗ КГКБ № 4, г. КемеровоФГБОУ ВО КемГМУ Минздрава России, г. КемеровоФГБОУ ВО КемГМУ Минздрава России, г. КемеровоФГБОУ ВО КемГМУ Минздрава России, г. КемеровоThe weakly positive Rh factor (Du phenotype) was described by physician and researcher Frederick Stratton in 1946 as a new variant of the antigen that reacts weakly with anti-D identifying sera. It is characterized by quantitative rather than qualitative differences, unlike the partial variant: with this type of Rh affiliation, the number of antigens on the erythrocyte is reduced. In most cases, this is due to genetic reasons. About 1 % of people have a weakly positive variant of the antigen D of the Rh factor – D weak, aka, «Du». More recently, such a phenotype was defined as negative. With conventional methods for determining Rh affiliation, it was previously difficult to identify a «weak» antigen. But with the use of new immunogenetic methods, it is not difficult to determine the presence of «weakly positive» Rh. The presented article describes a clinical case of pregnancy and childbirth in a woman with a weakly positive Rh factor.https://mednauki.ru/index.php/MD/article/view/1149беременностьродыслабоположительный резус-фактор |
spellingShingle | Юлия Сергеевна Фролова Екатерина Владимировна Грищенко Светлана Ивановна Елгина Елена Владимировна Рудаева Кира Борисовна Мозес WEAKLY POSITIVE RH FACTOR, DIAGNOSED FOR THE FIRST TIME IN A WOMAN DURING PREGNANCY (CLINICAL CASE) Мать и дитя в Кузбассе беременность роды слабоположительный резус-фактор |
title | WEAKLY POSITIVE RH FACTOR, DIAGNOSED FOR THE FIRST TIME IN A WOMAN DURING PREGNANCY (CLINICAL CASE) |
title_full | WEAKLY POSITIVE RH FACTOR, DIAGNOSED FOR THE FIRST TIME IN A WOMAN DURING PREGNANCY (CLINICAL CASE) |
title_fullStr | WEAKLY POSITIVE RH FACTOR, DIAGNOSED FOR THE FIRST TIME IN A WOMAN DURING PREGNANCY (CLINICAL CASE) |
title_full_unstemmed | WEAKLY POSITIVE RH FACTOR, DIAGNOSED FOR THE FIRST TIME IN A WOMAN DURING PREGNANCY (CLINICAL CASE) |
title_short | WEAKLY POSITIVE RH FACTOR, DIAGNOSED FOR THE FIRST TIME IN A WOMAN DURING PREGNANCY (CLINICAL CASE) |
title_sort | weakly positive rh factor diagnosed for the first time in a woman during pregnancy clinical case |
topic | беременность роды слабоположительный резус-фактор |
url | https://mednauki.ru/index.php/MD/article/view/1149 |
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