Advanced-stage Endometrial Stromal Sarcoma Presenting as Primary Infertility in a Young Nulligravida: A Case Report
Endometrial stromal sarcoma (ESS) rarely causes infertility in young women. We report a nulligravida in her 30s who presented with primary infertility of 15 years. Hysteroscopy revealed a submucosal necrotic fibroid polyp. Ultrasonography detected multiple intramural fibroids. Open myomectomy with p...
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Galenos Publishing House
2022-09-01
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| Series: | Medeniyet Medical Journal |
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| Online Access: | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=medeniyet&un=MEDJ-16132 |
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| author | Ankita PATTANAIK Jasmina BEGUM Sweta SINGH Deepthy BALAKRISHNAN Suvradeep MITRA |
| author_facet | Ankita PATTANAIK Jasmina BEGUM Sweta SINGH Deepthy BALAKRISHNAN Suvradeep MITRA |
| author_sort | Ankita PATTANAIK |
| collection | DOAJ |
| description | Endometrial stromal sarcoma (ESS) rarely causes infertility in young women. We report a nulligravida in her 30s who presented with primary infertility of 15 years. Hysteroscopy revealed a submucosal necrotic fibroid polyp. Ultrasonography detected multiple intramural fibroids. Open myomectomy with polypectomy was performed. Histopathology revealed low-grade ESS (LGESS) within the fibroid polyp. Subsequently, the patient underwent completion surgery. Her final diagnosis was estrogen-receptor positive LGESS stage IIIB, and she was suggested anastrozole adjuvant therapy and long-term surveillance. ESS with abnormal perimenopausal bleeding, though the most common presentation, may not always observed. Hence, a high index of suspicion of ESS should always be kept as a differential diagnosis in uterine fibroid polyp, though rare. Considering the scarcity of more extensive studies on ESS, reporting of cases will aid in formulating management protocols. |
| format | Article |
| id | doaj-art-4343c283ef814407a09a68d8f1c2d46d |
| institution | Kabale University |
| issn | 2149-2042 2149-4606 |
| language | English |
| publishDate | 2022-09-01 |
| publisher | Galenos Publishing House |
| record_format | Article |
| series | Medeniyet Medical Journal |
| spelling | doaj-art-4343c283ef814407a09a68d8f1c2d46d2025-01-30T07:10:56ZengGalenos Publishing HouseMedeniyet Medical Journal2149-20422149-46062022-09-0137329329710.4274/MMJ.galenos.2022.16132MEDJ-16132Advanced-stage Endometrial Stromal Sarcoma Presenting as Primary Infertility in a Young Nulligravida: A Case ReportAnkita PATTANAIK0Jasmina BEGUM1Sweta SINGH2Deepthy BALAKRISHNAN3Suvradeep MITRA4All India Institute of Medical Sciences, Department of Obstetrics and Gynecology, Bhubaneswar, IndiaAll India Institute of Medical Sciences, Department of Obstetrics and Gynecology, Bhubaneswar, IndiaAll India Institute of Medical Sciences, Department of Obstetrics and Gynecology, Bhubaneswar, IndiaAll India Institute of Medical Sciences, Department of Obstetrics and Gynecology, Bhubaneswar, IndiaAll India Institute of Medical Sciences, Department of Pathology, Bhubaneswar, IndiaEndometrial stromal sarcoma (ESS) rarely causes infertility in young women. We report a nulligravida in her 30s who presented with primary infertility of 15 years. Hysteroscopy revealed a submucosal necrotic fibroid polyp. Ultrasonography detected multiple intramural fibroids. Open myomectomy with polypectomy was performed. Histopathology revealed low-grade ESS (LGESS) within the fibroid polyp. Subsequently, the patient underwent completion surgery. Her final diagnosis was estrogen-receptor positive LGESS stage IIIB, and she was suggested anastrozole adjuvant therapy and long-term surveillance. ESS with abnormal perimenopausal bleeding, though the most common presentation, may not always observed. Hence, a high index of suspicion of ESS should always be kept as a differential diagnosis in uterine fibroid polyp, though rare. Considering the scarcity of more extensive studies on ESS, reporting of cases will aid in formulating management protocols.https://jag.journalagent.com/z4/download_fulltext.asp?pdir=medeniyet&un=MEDJ-16132uterine sarcomaendometrial stromal sarcomalow-grade endometrial stromal sarcomabilateral salpingo-oophorectomyadjuvant radiation hormonal therapy |
| spellingShingle | Ankita PATTANAIK Jasmina BEGUM Sweta SINGH Deepthy BALAKRISHNAN Suvradeep MITRA Advanced-stage Endometrial Stromal Sarcoma Presenting as Primary Infertility in a Young Nulligravida: A Case Report Medeniyet Medical Journal uterine sarcoma endometrial stromal sarcoma low-grade endometrial stromal sarcoma bilateral salpingo-oophorectomy adjuvant radiation hormonal therapy |
| title | Advanced-stage Endometrial Stromal Sarcoma Presenting as Primary Infertility in a Young Nulligravida: A Case Report |
| title_full | Advanced-stage Endometrial Stromal Sarcoma Presenting as Primary Infertility in a Young Nulligravida: A Case Report |
| title_fullStr | Advanced-stage Endometrial Stromal Sarcoma Presenting as Primary Infertility in a Young Nulligravida: A Case Report |
| title_full_unstemmed | Advanced-stage Endometrial Stromal Sarcoma Presenting as Primary Infertility in a Young Nulligravida: A Case Report |
| title_short | Advanced-stage Endometrial Stromal Sarcoma Presenting as Primary Infertility in a Young Nulligravida: A Case Report |
| title_sort | advanced stage endometrial stromal sarcoma presenting as primary infertility in a young nulligravida a case report |
| topic | uterine sarcoma endometrial stromal sarcoma low-grade endometrial stromal sarcoma bilateral salpingo-oophorectomy adjuvant radiation hormonal therapy |
| url | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=medeniyet&un=MEDJ-16132 |
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