Current Research Progress on Long Noncoding RNAs Associated with Hepatocellular Carcinoma
Hepatocellular carcinoma (HCC) is the second leading cause of mortality among cancers. It has been found that long noncoding RNAs (lncRNAs) are involved in many human cancers, including liver cancer. It has been identified that carcinogenic and tumor-suppressing lncRNAs are associated with complex p...
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Format: | Article |
Language: | English |
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Wiley
2019-01-01
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Series: | Analytical Cellular Pathology |
Online Access: | http://dx.doi.org/10.1155/2019/1534607 |
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author | Haihong Shi Yuxin Xu Xin Yi Dandan Fang Xia Hou |
author_facet | Haihong Shi Yuxin Xu Xin Yi Dandan Fang Xia Hou |
author_sort | Haihong Shi |
collection | DOAJ |
description | Hepatocellular carcinoma (HCC) is the second leading cause of mortality among cancers. It has been found that long noncoding RNAs (lncRNAs) are involved in many human cancers, including liver cancer. It has been identified that carcinogenic and tumor-suppressing lncRNAs are associated with complex processes in liver cancer. These lncRNAs may participate in a variety of pathological and biological activities, such as cell proliferation, apoptosis, invasion, and metastasis. Here, we review the regulation and function of lncRNA in liver cancer and evaluate the potential of lncRNA as a new goal for liver cancer. |
format | Article |
id | doaj-art-432166e2000948bea444de222f81a6df |
institution | Kabale University |
issn | 2210-7177 2210-7185 |
language | English |
publishDate | 2019-01-01 |
publisher | Wiley |
record_format | Article |
series | Analytical Cellular Pathology |
spelling | doaj-art-432166e2000948bea444de222f81a6df2025-02-03T05:45:49ZengWileyAnalytical Cellular Pathology2210-71772210-71852019-01-01201910.1155/2019/15346071534607Current Research Progress on Long Noncoding RNAs Associated with Hepatocellular CarcinomaHaihong Shi0Yuxin Xu1Xin Yi2Dandan Fang3Xia Hou4Department of Biochemistry and Molecular Biology, Jiamusi University School of Basic Medicine, Jiamusi, Heilongjiang 154007, ChinaJiamusi Maternal and Child Health Hospital, Jiamusi, Heilongjiang 154001, ChinaDepartment of Biochemistry and Molecular Biology, Jiamusi University School of Basic Medicine, Jiamusi, Heilongjiang 154007, ChinaHospital of Traditional Chinese Medicine of Qiqihar, Qiqihar, Heilongjiang 161000, ChinaDepartment of Biochemistry and Molecular Biology, Jiamusi University School of Basic Medicine, Jiamusi, Heilongjiang 154007, ChinaHepatocellular carcinoma (HCC) is the second leading cause of mortality among cancers. It has been found that long noncoding RNAs (lncRNAs) are involved in many human cancers, including liver cancer. It has been identified that carcinogenic and tumor-suppressing lncRNAs are associated with complex processes in liver cancer. These lncRNAs may participate in a variety of pathological and biological activities, such as cell proliferation, apoptosis, invasion, and metastasis. Here, we review the regulation and function of lncRNA in liver cancer and evaluate the potential of lncRNA as a new goal for liver cancer.http://dx.doi.org/10.1155/2019/1534607 |
spellingShingle | Haihong Shi Yuxin Xu Xin Yi Dandan Fang Xia Hou Current Research Progress on Long Noncoding RNAs Associated with Hepatocellular Carcinoma Analytical Cellular Pathology |
title | Current Research Progress on Long Noncoding RNAs Associated with Hepatocellular Carcinoma |
title_full | Current Research Progress on Long Noncoding RNAs Associated with Hepatocellular Carcinoma |
title_fullStr | Current Research Progress on Long Noncoding RNAs Associated with Hepatocellular Carcinoma |
title_full_unstemmed | Current Research Progress on Long Noncoding RNAs Associated with Hepatocellular Carcinoma |
title_short | Current Research Progress on Long Noncoding RNAs Associated with Hepatocellular Carcinoma |
title_sort | current research progress on long noncoding rnas associated with hepatocellular carcinoma |
url | http://dx.doi.org/10.1155/2019/1534607 |
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