Current Research Progress on Long Noncoding RNAs Associated with Hepatocellular Carcinoma

Hepatocellular carcinoma (HCC) is the second leading cause of mortality among cancers. It has been found that long noncoding RNAs (lncRNAs) are involved in many human cancers, including liver cancer. It has been identified that carcinogenic and tumor-suppressing lncRNAs are associated with complex p...

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Main Authors: Haihong Shi, Yuxin Xu, Xin Yi, Dandan Fang, Xia Hou
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Analytical Cellular Pathology
Online Access:http://dx.doi.org/10.1155/2019/1534607
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author Haihong Shi
Yuxin Xu
Xin Yi
Dandan Fang
Xia Hou
author_facet Haihong Shi
Yuxin Xu
Xin Yi
Dandan Fang
Xia Hou
author_sort Haihong Shi
collection DOAJ
description Hepatocellular carcinoma (HCC) is the second leading cause of mortality among cancers. It has been found that long noncoding RNAs (lncRNAs) are involved in many human cancers, including liver cancer. It has been identified that carcinogenic and tumor-suppressing lncRNAs are associated with complex processes in liver cancer. These lncRNAs may participate in a variety of pathological and biological activities, such as cell proliferation, apoptosis, invasion, and metastasis. Here, we review the regulation and function of lncRNA in liver cancer and evaluate the potential of lncRNA as a new goal for liver cancer.
format Article
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institution Kabale University
issn 2210-7177
2210-7185
language English
publishDate 2019-01-01
publisher Wiley
record_format Article
series Analytical Cellular Pathology
spelling doaj-art-432166e2000948bea444de222f81a6df2025-02-03T05:45:49ZengWileyAnalytical Cellular Pathology2210-71772210-71852019-01-01201910.1155/2019/15346071534607Current Research Progress on Long Noncoding RNAs Associated with Hepatocellular CarcinomaHaihong Shi0Yuxin Xu1Xin Yi2Dandan Fang3Xia Hou4Department of Biochemistry and Molecular Biology, Jiamusi University School of Basic Medicine, Jiamusi, Heilongjiang 154007, ChinaJiamusi Maternal and Child Health Hospital, Jiamusi, Heilongjiang 154001, ChinaDepartment of Biochemistry and Molecular Biology, Jiamusi University School of Basic Medicine, Jiamusi, Heilongjiang 154007, ChinaHospital of Traditional Chinese Medicine of Qiqihar, Qiqihar, Heilongjiang 161000, ChinaDepartment of Biochemistry and Molecular Biology, Jiamusi University School of Basic Medicine, Jiamusi, Heilongjiang 154007, ChinaHepatocellular carcinoma (HCC) is the second leading cause of mortality among cancers. It has been found that long noncoding RNAs (lncRNAs) are involved in many human cancers, including liver cancer. It has been identified that carcinogenic and tumor-suppressing lncRNAs are associated with complex processes in liver cancer. These lncRNAs may participate in a variety of pathological and biological activities, such as cell proliferation, apoptosis, invasion, and metastasis. Here, we review the regulation and function of lncRNA in liver cancer and evaluate the potential of lncRNA as a new goal for liver cancer.http://dx.doi.org/10.1155/2019/1534607
spellingShingle Haihong Shi
Yuxin Xu
Xin Yi
Dandan Fang
Xia Hou
Current Research Progress on Long Noncoding RNAs Associated with Hepatocellular Carcinoma
Analytical Cellular Pathology
title Current Research Progress on Long Noncoding RNAs Associated with Hepatocellular Carcinoma
title_full Current Research Progress on Long Noncoding RNAs Associated with Hepatocellular Carcinoma
title_fullStr Current Research Progress on Long Noncoding RNAs Associated with Hepatocellular Carcinoma
title_full_unstemmed Current Research Progress on Long Noncoding RNAs Associated with Hepatocellular Carcinoma
title_short Current Research Progress on Long Noncoding RNAs Associated with Hepatocellular Carcinoma
title_sort current research progress on long noncoding rnas associated with hepatocellular carcinoma
url http://dx.doi.org/10.1155/2019/1534607
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AT xinyi currentresearchprogressonlongnoncodingrnasassociatedwithhepatocellularcarcinoma
AT dandanfang currentresearchprogressonlongnoncodingrnasassociatedwithhepatocellularcarcinoma
AT xiahou currentresearchprogressonlongnoncodingrnasassociatedwithhepatocellularcarcinoma