Fatal Cerebral Edema in a Young Adult with Diabetic Ketoacidosis: Blame the Bicarbonate?
Cerebral edema is a devastating complication of DKA which is extremely rare in adults but is the leading cause of diabetes-related death in the pediatric population. Newly diagnosed diabetes, younger age, first episode of DKA, severity of DKA at presentation, and administration of bicarbonate are pr...
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | Case Reports in Critical Care |
| Online Access: | http://dx.doi.org/10.1155/2020/5917459 |
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| _version_ | 1832566534266945536 |
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| author | Sameera Natarajan Radhika Kulkarni Apoorva Tangri |
| author_facet | Sameera Natarajan Radhika Kulkarni Apoorva Tangri |
| author_sort | Sameera Natarajan |
| collection | DOAJ |
| description | Cerebral edema is a devastating complication of DKA which is extremely rare in adults but is the leading cause of diabetes-related death in the pediatric population. Newly diagnosed diabetes, younger age, first episode of DKA, severity of DKA at presentation, and administration of bicarbonate are predictive of cerebral edema in DKA. We present a case of a young adult with DKA as the presenting symptom of diabetes, whose clinical course was complicated by renal failure, refractory shock, and cerebral edema. This case addresses the controversy surrounding bicarbonate therapy in DKA and its possible role in the development of a rare fatal complication of DKA. |
| format | Article |
| id | doaj-art-430264395ee545989a1a80967c278bcc |
| institution | Kabale University |
| issn | 2090-6420 2090-6439 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Critical Care |
| spelling | doaj-art-430264395ee545989a1a80967c278bcc2025-02-03T01:03:48ZengWileyCase Reports in Critical Care2090-64202090-64392020-01-01202010.1155/2020/59174595917459Fatal Cerebral Edema in a Young Adult with Diabetic Ketoacidosis: Blame the Bicarbonate?Sameera Natarajan0Radhika Kulkarni1Apoorva Tangri2Advocate Illinois Masonic Medical Center, 836 W Wellington Ave., Chicago, IL 60657, USAUniversity of Connecticut: UConn Health, 263 Farmington Ave., Farmington, CT 06030, USARush University Medical Center, 1750 W Harrison St., Jelke Building South, Suite 444, Chicago, IL 60612, USACerebral edema is a devastating complication of DKA which is extremely rare in adults but is the leading cause of diabetes-related death in the pediatric population. Newly diagnosed diabetes, younger age, first episode of DKA, severity of DKA at presentation, and administration of bicarbonate are predictive of cerebral edema in DKA. We present a case of a young adult with DKA as the presenting symptom of diabetes, whose clinical course was complicated by renal failure, refractory shock, and cerebral edema. This case addresses the controversy surrounding bicarbonate therapy in DKA and its possible role in the development of a rare fatal complication of DKA.http://dx.doi.org/10.1155/2020/5917459 |
| spellingShingle | Sameera Natarajan Radhika Kulkarni Apoorva Tangri Fatal Cerebral Edema in a Young Adult with Diabetic Ketoacidosis: Blame the Bicarbonate? Case Reports in Critical Care |
| title | Fatal Cerebral Edema in a Young Adult with Diabetic Ketoacidosis: Blame the Bicarbonate? |
| title_full | Fatal Cerebral Edema in a Young Adult with Diabetic Ketoacidosis: Blame the Bicarbonate? |
| title_fullStr | Fatal Cerebral Edema in a Young Adult with Diabetic Ketoacidosis: Blame the Bicarbonate? |
| title_full_unstemmed | Fatal Cerebral Edema in a Young Adult with Diabetic Ketoacidosis: Blame the Bicarbonate? |
| title_short | Fatal Cerebral Edema in a Young Adult with Diabetic Ketoacidosis: Blame the Bicarbonate? |
| title_sort | fatal cerebral edema in a young adult with diabetic ketoacidosis blame the bicarbonate |
| url | http://dx.doi.org/10.1155/2020/5917459 |
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