NK cell-specific knockout of UTX modulates pulmonary metastasis of melanoma in a sex-dependent manner

Objective‍ ‍To explore the role of X chromosome encoded epigenetic regulator UTX in NK cell-mediated anti-tumor activity. Methods‍ ‍Male Ncr1-iCre mice were crossed with female UTXfl/fl mice to generate F1 Ncr1-iCre+UTXfl/- male mice, which were further crossed with female UTXfl/fl mice to obtain ma...

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Bibliographic Details
Main Authors: HUANG Pei, WANG Hongchen, HUANG He
Format: Article
Language:zho
Published: Editorial Office of Journal of Army Medical University 2025-04-01
Series:陆军军医大学学报
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Online Access:https://aammt.tmmu.edu.cn/html/202411078.html
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