Sugar Alcohols, Caries Incidence, and Remineralization of Caries Lesions: A Literature Review

Remineralization of minor enamel defects is a normal physiological process that is well known to clinicians and researchers in dentistry and oral biology. This process can be facilitated by various dietary and oral hygiene procedures and may also concern dentin caries lesions. Dental caries is rever...

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Main Author: Kauko K. Mäkinen
Format: Article
Language:English
Published: Wiley 2010-01-01
Series:International Journal of Dentistry
Online Access:http://dx.doi.org/10.1155/2010/981072
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author Kauko K. Mäkinen
author_facet Kauko K. Mäkinen
author_sort Kauko K. Mäkinen
collection DOAJ
description Remineralization of minor enamel defects is a normal physiological process that is well known to clinicians and researchers in dentistry and oral biology. This process can be facilitated by various dietary and oral hygiene procedures and may also concern dentin caries lesions. Dental caries is reversible if detected and treated sufficiently early. Habitual use of xylitol, a sugar alcohol of the pentitol type, can be associated with significant reduction in caries incidence and with tooth remineralization. Other dietary polyols that can remarkably lower the incidence of caries include erythritol which is a tetritol-type alditol. Based on known molecular parameters of simple dietary alditols, it is conceivable to predict that their efficacy in caries prevention will follow the homologous series, that is, that the number of OH-groups present in the alditol molecule will determine the efficacy as follows: erythritol≥xylitol>sorbitol. The possible difference between erythritol and xylitol must be confirmed in future clinical trials.
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spelling doaj-art-42df361f2b13497d90872e133a2ec5a32025-02-03T06:00:57ZengWileyInternational Journal of Dentistry1687-87281687-87362010-01-01201010.1155/2010/981072981072Sugar Alcohols, Caries Incidence, and Remineralization of Caries Lesions: A Literature ReviewKauko K. Mäkinen0Institute of Dentistry, University of Turku, Lemminkäisenkatu 2, 20520 Turku, FinlandRemineralization of minor enamel defects is a normal physiological process that is well known to clinicians and researchers in dentistry and oral biology. This process can be facilitated by various dietary and oral hygiene procedures and may also concern dentin caries lesions. Dental caries is reversible if detected and treated sufficiently early. Habitual use of xylitol, a sugar alcohol of the pentitol type, can be associated with significant reduction in caries incidence and with tooth remineralization. Other dietary polyols that can remarkably lower the incidence of caries include erythritol which is a tetritol-type alditol. Based on known molecular parameters of simple dietary alditols, it is conceivable to predict that their efficacy in caries prevention will follow the homologous series, that is, that the number of OH-groups present in the alditol molecule will determine the efficacy as follows: erythritol≥xylitol>sorbitol. The possible difference between erythritol and xylitol must be confirmed in future clinical trials.http://dx.doi.org/10.1155/2010/981072
spellingShingle Kauko K. Mäkinen
Sugar Alcohols, Caries Incidence, and Remineralization of Caries Lesions: A Literature Review
International Journal of Dentistry
title Sugar Alcohols, Caries Incidence, and Remineralization of Caries Lesions: A Literature Review
title_full Sugar Alcohols, Caries Incidence, and Remineralization of Caries Lesions: A Literature Review
title_fullStr Sugar Alcohols, Caries Incidence, and Remineralization of Caries Lesions: A Literature Review
title_full_unstemmed Sugar Alcohols, Caries Incidence, and Remineralization of Caries Lesions: A Literature Review
title_short Sugar Alcohols, Caries Incidence, and Remineralization of Caries Lesions: A Literature Review
title_sort sugar alcohols caries incidence and remineralization of caries lesions a literature review
url http://dx.doi.org/10.1155/2010/981072
work_keys_str_mv AT kaukokmakinen sugaralcoholscariesincidenceandremineralizationofcarieslesionsaliteraturereview