Natural Protein Films from Textile Waste for Wound Healing and Wound Dressing Applications

In recent years, several studies have focused on the development of sustainable, biocompatible, and biodegradable films with potential applications in wound healing and wound dressing systems. Natural macromolecules, particularly proteins, have emerged as attractive alternatives to synthetic polymer...

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Main Authors: Livia Ottaviano, Sara Buoso, Roberto Zamboni, Giovanna Sotgiu, Tamara Posati
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Journal of Functional Biomaterials
Subjects:
Online Access:https://www.mdpi.com/2079-4983/16/1/20
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author Livia Ottaviano
Sara Buoso
Roberto Zamboni
Giovanna Sotgiu
Tamara Posati
author_facet Livia Ottaviano
Sara Buoso
Roberto Zamboni
Giovanna Sotgiu
Tamara Posati
author_sort Livia Ottaviano
collection DOAJ
description In recent years, several studies have focused on the development of sustainable, biocompatible, and biodegradable films with potential applications in wound healing and wound dressing systems. Natural macromolecules, particularly proteins, have emerged as attractive alternatives to synthetic polymers due to their biocompatibility, biodegradability, low immunogenicity, and adaptability. Among these proteins, keratin, extracted from waste wool, and fibroin, derived from <i>Bombyx mori</i> cocoons, exhibit exceptional properties such as mechanical strength, cell adhesion capabilities, and suitability for various fabrication methods. These proteins can also be functionalized with antimicrobial, antioxidant, and anti-inflammatory compounds, making them highly versatile for biomedical applications. This review highlights the promising potential of keratin- and fibroin-based films as innovative platforms for wound healing, emphasizing their advantages and the prospects they offer in creating next-generation wound dressing devices.
format Article
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institution Kabale University
issn 2079-4983
language English
publishDate 2025-01-01
publisher MDPI AG
record_format Article
series Journal of Functional Biomaterials
spelling doaj-art-42c45c7c0d5f4d8788decef47d7a6b2a2025-01-24T13:36:09ZengMDPI AGJournal of Functional Biomaterials2079-49832025-01-011612010.3390/jfb16010020Natural Protein Films from Textile Waste for Wound Healing and Wound Dressing ApplicationsLivia Ottaviano0Sara Buoso1Roberto Zamboni2Giovanna Sotgiu3Tamara Posati4National Research Council, Institute for Organic Synthesis and Photoreactivity (CNR-ISOF), Via P. Gobetti 101, 40129 Bologna, ItalyKerline srl, Via Gobetti 101, 40129 Bologna, ItalyNational Research Council, Institute for Organic Synthesis and Photoreactivity (CNR-ISOF), Via P. Gobetti 101, 40129 Bologna, ItalyNational Research Council, Institute for Organic Synthesis and Photoreactivity (CNR-ISOF), Via P. Gobetti 101, 40129 Bologna, ItalyNational Research Council, Institute for Organic Synthesis and Photoreactivity (CNR-ISOF), Via P. Gobetti 101, 40129 Bologna, ItalyIn recent years, several studies have focused on the development of sustainable, biocompatible, and biodegradable films with potential applications in wound healing and wound dressing systems. Natural macromolecules, particularly proteins, have emerged as attractive alternatives to synthetic polymers due to their biocompatibility, biodegradability, low immunogenicity, and adaptability. Among these proteins, keratin, extracted from waste wool, and fibroin, derived from <i>Bombyx mori</i> cocoons, exhibit exceptional properties such as mechanical strength, cell adhesion capabilities, and suitability for various fabrication methods. These proteins can also be functionalized with antimicrobial, antioxidant, and anti-inflammatory compounds, making them highly versatile for biomedical applications. This review highlights the promising potential of keratin- and fibroin-based films as innovative platforms for wound healing, emphasizing their advantages and the prospects they offer in creating next-generation wound dressing devices.https://www.mdpi.com/2079-4983/16/1/20silk fibroin filmskeratin filmswound healingwound dressing
spellingShingle Livia Ottaviano
Sara Buoso
Roberto Zamboni
Giovanna Sotgiu
Tamara Posati
Natural Protein Films from Textile Waste for Wound Healing and Wound Dressing Applications
Journal of Functional Biomaterials
silk fibroin films
keratin films
wound healing
wound dressing
title Natural Protein Films from Textile Waste for Wound Healing and Wound Dressing Applications
title_full Natural Protein Films from Textile Waste for Wound Healing and Wound Dressing Applications
title_fullStr Natural Protein Films from Textile Waste for Wound Healing and Wound Dressing Applications
title_full_unstemmed Natural Protein Films from Textile Waste for Wound Healing and Wound Dressing Applications
title_short Natural Protein Films from Textile Waste for Wound Healing and Wound Dressing Applications
title_sort natural protein films from textile waste for wound healing and wound dressing applications
topic silk fibroin films
keratin films
wound healing
wound dressing
url https://www.mdpi.com/2079-4983/16/1/20
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AT robertozamboni naturalproteinfilmsfromtextilewasteforwoundhealingandwounddressingapplications
AT giovannasotgiu naturalproteinfilmsfromtextilewasteforwoundhealingandwounddressingapplications
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