Focus on Basal Cell Carcinoma
Nonmelanoma skin cancers (NMSCs), which include basal and squamous cell cancers are the most common human cancers. BCCs have a relatively low metastatic rate and slow growth and are frequently underreported. Whilst there is a definite role of sunexposure in the pathogenesis of BCC, several additiona...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2011-01-01
|
| Series: | Journal of Skin Cancer |
| Online Access: | http://dx.doi.org/10.1155/2011/328615 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832556738124972032 |
|---|---|
| author | Venura Samarasinghe Vishal Madan John T. Lear |
| author_facet | Venura Samarasinghe Vishal Madan John T. Lear |
| author_sort | Venura Samarasinghe |
| collection | DOAJ |
| description | Nonmelanoma skin cancers (NMSCs), which include basal and squamous cell cancers are the most common human cancers. BCCs have a relatively low metastatic rate and slow growth and are frequently underreported. Whilst there is a definite role of sunexposure in the pathogenesis of BCC, several additional complex genotypic, phenotypic and environmental factors are contributory.
The high prevalence and the frequent occurrence of multiple primary BCC in affected individuals make them an important public health problem. This has led to a substantial increase in search for newer noninvasive treatments for BCC. Surgical excision with predetermined margins remains the mainstay treatment for most BCC. Of the newer non-invasive treatments only photodynamic therapy and topical imiquimod have become established in the treatment of certain BCC subtypes, while the search for other more effective and tissue salvaging therapies continues. This paper focuses on the pathogenesis and management of BCC. |
| format | Article |
| id | doaj-art-42c2f06fbb884e9a84b631eef2429be2 |
| institution | Kabale University |
| issn | 2090-2905 2090-2913 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Skin Cancer |
| spelling | doaj-art-42c2f06fbb884e9a84b631eef2429be22025-02-03T05:44:26ZengWileyJournal of Skin Cancer2090-29052090-29132011-01-01201110.1155/2011/328615328615Focus on Basal Cell CarcinomaVenura Samarasinghe0Vishal Madan1John T. Lear2Manchester Royal Infirmary, Central Manchester and Manchester Childrens' Hospital NHS Trust, Oxford Road, Manchester M13 9WL, UKManchester Royal Infirmary, Central Manchester and Manchester Childrens' Hospital NHS Trust, Oxford Road, Manchester M13 9WL, UKManchester Royal Infirmary, Central Manchester and Manchester Childrens' Hospital NHS Trust, Oxford Road, Manchester M13 9WL, UKNonmelanoma skin cancers (NMSCs), which include basal and squamous cell cancers are the most common human cancers. BCCs have a relatively low metastatic rate and slow growth and are frequently underreported. Whilst there is a definite role of sunexposure in the pathogenesis of BCC, several additional complex genotypic, phenotypic and environmental factors are contributory. The high prevalence and the frequent occurrence of multiple primary BCC in affected individuals make them an important public health problem. This has led to a substantial increase in search for newer noninvasive treatments for BCC. Surgical excision with predetermined margins remains the mainstay treatment for most BCC. Of the newer non-invasive treatments only photodynamic therapy and topical imiquimod have become established in the treatment of certain BCC subtypes, while the search for other more effective and tissue salvaging therapies continues. This paper focuses on the pathogenesis and management of BCC.http://dx.doi.org/10.1155/2011/328615 |
| spellingShingle | Venura Samarasinghe Vishal Madan John T. Lear Focus on Basal Cell Carcinoma Journal of Skin Cancer |
| title | Focus on Basal Cell Carcinoma |
| title_full | Focus on Basal Cell Carcinoma |
| title_fullStr | Focus on Basal Cell Carcinoma |
| title_full_unstemmed | Focus on Basal Cell Carcinoma |
| title_short | Focus on Basal Cell Carcinoma |
| title_sort | focus on basal cell carcinoma |
| url | http://dx.doi.org/10.1155/2011/328615 |
| work_keys_str_mv | AT venurasamarasinghe focusonbasalcellcarcinoma AT vishalmadan focusonbasalcellcarcinoma AT johntlear focusonbasalcellcarcinoma |