Lupus Flare: An Uncommon Presentation of Disseminated Gonorrhea

Gonorrhea is one of the most common sexually transmitted diseases in the US with 700,000 annual cases. Although most cases of gonorrhea are localized, approximately 0.5–3% become disseminated. Here we discuss a rare case of a patient with systemic lupus erythematosus (SLE) who developed septic shock...

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Main Authors: Uyen To, Joyce Kim, David Chia
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2014/626095
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author Uyen To
Joyce Kim
David Chia
author_facet Uyen To
Joyce Kim
David Chia
author_sort Uyen To
collection DOAJ
description Gonorrhea is one of the most common sexually transmitted diseases in the US with 700,000 annual cases. Although most cases of gonorrhea are localized, approximately 0.5–3% become disseminated. Here we discuss a rare case of a patient with systemic lupus erythematosus (SLE) who developed septic shock from disseminated gonorrhea infection (DGI). Our patient is a 24-year-old woman with SLE, mixed connective tissue disease with cutaneous vasculitis, and lupus nephritis who presented with several weeks of malaise and generalized body aches associated with a diffuse rash along her fingers, palms, and trunk. Infectious workup was unrevealing with the exception of a positive gonorrhea test obtained from a cervical swab. Given her symptoms of tenosynovitis, the appearance of her skin lesions, and her positive gonorrhea test, she was diagnosed with septic shock secondary to DGI. With antibiotic treatment, the patient reported a dramatic improvement of the pain in her swollen joints and her rash receded. Patients diagnosed with SLE carry an increased risk of gonorrhea regardless of whether or not they are being treated for their SLE. Although it is well-documented that SLE is associated with severe DGI, few describe it resulting in overt septic shock.
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spelling doaj-art-42b8587c499a4be8b304821e569baa822025-02-03T05:48:08ZengWileyCase Reports in Medicine1687-96271687-96352014-01-01201410.1155/2014/626095626095Lupus Flare: An Uncommon Presentation of Disseminated GonorrheaUyen To0Joyce Kim1David Chia2Yale School of Medicine, 333 Cedar Street, New Haven, CT 06510, USAYale School of Medicine, 333 Cedar Street, New Haven, CT 06510, USAYale School of Medicine, 333 Cedar Street, New Haven, CT 06510, USAGonorrhea is one of the most common sexually transmitted diseases in the US with 700,000 annual cases. Although most cases of gonorrhea are localized, approximately 0.5–3% become disseminated. Here we discuss a rare case of a patient with systemic lupus erythematosus (SLE) who developed septic shock from disseminated gonorrhea infection (DGI). Our patient is a 24-year-old woman with SLE, mixed connective tissue disease with cutaneous vasculitis, and lupus nephritis who presented with several weeks of malaise and generalized body aches associated with a diffuse rash along her fingers, palms, and trunk. Infectious workup was unrevealing with the exception of a positive gonorrhea test obtained from a cervical swab. Given her symptoms of tenosynovitis, the appearance of her skin lesions, and her positive gonorrhea test, she was diagnosed with septic shock secondary to DGI. With antibiotic treatment, the patient reported a dramatic improvement of the pain in her swollen joints and her rash receded. Patients diagnosed with SLE carry an increased risk of gonorrhea regardless of whether or not they are being treated for their SLE. Although it is well-documented that SLE is associated with severe DGI, few describe it resulting in overt septic shock.http://dx.doi.org/10.1155/2014/626095
spellingShingle Uyen To
Joyce Kim
David Chia
Lupus Flare: An Uncommon Presentation of Disseminated Gonorrhea
Case Reports in Medicine
title Lupus Flare: An Uncommon Presentation of Disseminated Gonorrhea
title_full Lupus Flare: An Uncommon Presentation of Disseminated Gonorrhea
title_fullStr Lupus Flare: An Uncommon Presentation of Disseminated Gonorrhea
title_full_unstemmed Lupus Flare: An Uncommon Presentation of Disseminated Gonorrhea
title_short Lupus Flare: An Uncommon Presentation of Disseminated Gonorrhea
title_sort lupus flare an uncommon presentation of disseminated gonorrhea
url http://dx.doi.org/10.1155/2014/626095
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