Structural insights into transcription regulation of the global OmpR/PhoB family regulator PhoP from Mycobacterium tuberculosis

Structural insights into transcription regulation of the global OmpR/PhoB family regulator PhoP from Mycobacterium tuberculosis

Abstract As a global transcription activator or repressor, the representative OmpR/PhoB family response regulator PhoP plays a crucial role in regulating bacterial pathogenicity and stress adaptation. However, the molecular mechanisms underlying the transcriptional regulation that define its differe...

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Main Authors: Jing Shi, Zhenzhen Feng, Qian Song, Aijia Wen, Tianyu Liu, Liqiao Xu, Zonghang Ye, Simin Xu, Fei Gao, Liuxiang Xiao, Jiapeng Zhu, Kalyan Das, Guoping Zhao, Jie Li, Yu Feng, Wei Lin
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-56697-x
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https://doi.org/10.1038/s41467-025-56697-x

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