Frailty and outcomes of vascular access for hemodialysis – a scoping review

INTRODUCTION: Frailty is an age-related condition related to the decline of physiologic capacity and the increased vulnerability to stressors. It is associated with increased mortality, hospitalizations, and healthcare costs. Dialysis patients, due to age and comorbidities, are especially vulnerabl...

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Main Authors: Lara R. Dias, Leandro Nóbrega, Tiago Costa-Pereira, Joana Ferreira, Armando Mansilha, Luís Coentrão
Format: Article
Language:Portuguese
Published: Sociedade Portuguesa de Angiologia e Cirurgia Vascular 2025-01-01
Series:Angiologia e Cirurgia Vascular
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Online Access:https://acvjournal.com/index.php/acv/article/view/613
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author Lara R. Dias
Leandro Nóbrega
Tiago Costa-Pereira
Joana Ferreira
Armando Mansilha
Luís Coentrão
author_facet Lara R. Dias
Leandro Nóbrega
Tiago Costa-Pereira
Joana Ferreira
Armando Mansilha
Luís Coentrão
author_sort Lara R. Dias
collection DOAJ
description INTRODUCTION: Frailty is an age-related condition related to the decline of physiologic capacity and the increased vulnerability to stressors. It is associated with increased mortality, hospitalizations, and healthcare costs. Dialysis patients, due to age and comorbidities, are especially vulnerable to frailty. The aim of this review was to assess the impact of frailty on outcomes of vascular access for haemodialysis. METHODS: A search was conducted on PubMed, Scopus and Cochrane to identify articles reporting on frailty and outcomes of vascular access in dialysis patients. RESULTS: A total of seven studies were included. Patients included ranged from 40 to 41471, and frailty prevalence ranged from 24 to 53%. There was considerable heterogeneity in frailty assessment. Three studies reported higher mortality in frail patients. Frailty was also associated with recurring vascular access failure, higher risk of non-maturation and access thrombosis in included studies. Higher perioperative complications in frail patients were also reported. CONCLUSION: Frailty is associated with adverse outcomes of vascular access in dialysis patients, including thrombosis, longer time to functional use of access, and reintervention. Frail patients also have higher mortality after vascular access construction when compared to non-frail patients. Frailty assessment might be a valuable tool in shared decision-making regarding vascular access in dialysis population.
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institution Kabale University
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language Portuguese
publishDate 2025-01-01
publisher Sociedade Portuguesa de Angiologia e Cirurgia Vascular
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spelling doaj-art-42b4992d57394471a4fd14c95666e63b2025-01-29T23:21:00ZporSociedade Portuguesa de Angiologia e Cirurgia VascularAngiologia e Cirurgia Vascular1646-706X2183-00962025-01-0120310.48750/acv.613Frailty and outcomes of vascular access for hemodialysis – a scoping reviewLara R. Dias0Leandro Nóbrega1Tiago Costa-Pereira2Joana Ferreira3Armando Mansilha4Luís Coentrão5Department of Angiology and Vascular Surgery, Unidade Local de Saúde São João, Porto, Portugal;  Department of Surgery and Physiology, Faculty of Medicine, Porto University, Porto, PortugalDepartment of Angiology and Vascular Surgery, Unidade Local de Saúde São João, Porto, Portugal;  Department of Surgery and Physiology, Faculty of Medicine, Porto University, Porto, PortugalDepartment of Angiology and Vascular Surgery, Unidade Local de Saúde São João, Porto, Portugal;  Department of Surgery and Physiology, Faculty of Medicine, Porto University, Porto, PortugalDepartment of Angiology and Vascular Surgery, Unidade Local de Saúde São João, Porto, Portugal;  Department of Surgery and Physiology, Faculty of Medicine, Porto University, Porto, PortugalDepartment of Angiology and Vascular Surgery, Unidade Local de Saúde São João, Porto, Portugal;  Department of Surgery and Physiology, Faculty of Medicine, Porto University, Porto, PortugalNephrology Department, Unidade Local de Saúde São João, Porto, Portugal; Nephrology & Infectious Diseases R&D, i3S - Instituto de Investigação e Inovação em Saúde da Universidade do Porto, Porto, Portugal INTRODUCTION: Frailty is an age-related condition related to the decline of physiologic capacity and the increased vulnerability to stressors. It is associated with increased mortality, hospitalizations, and healthcare costs. Dialysis patients, due to age and comorbidities, are especially vulnerable to frailty. The aim of this review was to assess the impact of frailty on outcomes of vascular access for haemodialysis. METHODS: A search was conducted on PubMed, Scopus and Cochrane to identify articles reporting on frailty and outcomes of vascular access in dialysis patients. RESULTS: A total of seven studies were included. Patients included ranged from 40 to 41471, and frailty prevalence ranged from 24 to 53%. There was considerable heterogeneity in frailty assessment. Three studies reported higher mortality in frail patients. Frailty was also associated with recurring vascular access failure, higher risk of non-maturation and access thrombosis in included studies. Higher perioperative complications in frail patients were also reported. CONCLUSION: Frailty is associated with adverse outcomes of vascular access in dialysis patients, including thrombosis, longer time to functional use of access, and reintervention. Frail patients also have higher mortality after vascular access construction when compared to non-frail patients. Frailty assessment might be a valuable tool in shared decision-making regarding vascular access in dialysis population. https://acvjournal.com/index.php/acv/article/view/613Renal DialysisFrailtyDialysis AccessChronic Kidney Disease
spellingShingle Lara R. Dias
Leandro Nóbrega
Tiago Costa-Pereira
Joana Ferreira
Armando Mansilha
Luís Coentrão
Frailty and outcomes of vascular access for hemodialysis – a scoping review
Angiologia e Cirurgia Vascular
Renal Dialysis
Frailty
Dialysis Access
Chronic Kidney Disease
title Frailty and outcomes of vascular access for hemodialysis – a scoping review
title_full Frailty and outcomes of vascular access for hemodialysis – a scoping review
title_fullStr Frailty and outcomes of vascular access for hemodialysis – a scoping review
title_full_unstemmed Frailty and outcomes of vascular access for hemodialysis – a scoping review
title_short Frailty and outcomes of vascular access for hemodialysis – a scoping review
title_sort frailty and outcomes of vascular access for hemodialysis a scoping review
topic Renal Dialysis
Frailty
Dialysis Access
Chronic Kidney Disease
url https://acvjournal.com/index.php/acv/article/view/613
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