Increased Nuclear Transporter KPNA2 Contributes to Tumor Immune Evasion by Enhancing PD-L1 Expression in PDAC
Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest malignancies and is known for its high resistance and low response to treatment. Tumor immune evasion is a major stumbling block in designing effective anticancer therapeutic strategies. Karyopherin alpha 2 (KPNA2), a member of the nucl...
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Main Authors: | Kai-Xia Zhou, Shan Huang, Li-Peng Hu, Xue-Li Zhang, Wei-Ting Qin, Yan-Li Zhang, Lin-Li Yao, Yanqiu Yu, Yao-Qi Zhou, Lei Zhu, Jianguang Ji, Zhi-Gang Zhang |
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Format: | Article |
Language: | English |
Published: |
Wiley
2021-01-01
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Series: | Journal of Immunology Research |
Online Access: | http://dx.doi.org/10.1155/2021/6694392 |
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