Administration of Traditional Chinese Blood Circulation Activating Drugs for Microvascular Complications in Patients with Type 2 Diabetes Mellitus
Traditional Chinese medicine (TCM) is an important complementary strategy for treating diabetes mellitus (DM) in China. Traditional Chinese blood circulation activating drugs are intended to guide an overall approach to the prevention and treatment of microvascular complications of DM. The core mech...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Journal of Diabetes Research |
| Online Access: | http://dx.doi.org/10.1155/2016/1081657 |
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| author | Lisha He Han Wang Chengjuan Gu Xinhui He Linhua Zhao Xiaolin Tong |
| author_facet | Lisha He Han Wang Chengjuan Gu Xinhui He Linhua Zhao Xiaolin Tong |
| author_sort | Lisha He |
| collection | DOAJ |
| description | Traditional Chinese medicine (TCM) is an important complementary strategy for treating diabetes mellitus (DM) in China. Traditional Chinese blood circulation activating drugs are intended to guide an overall approach to the prevention and treatment of microvascular complications of DM. The core mechanism is related to the protection of the vascular endothelium and the basement membrane. Here, we reviewed the scientific evidence underpinning the use of blood circulation activating drugs to prevent and treat DM-induced microvascular complications, including diabetic nephropathy (DN), diabetic peripheral neuropathy (DPN), and diabetic retinopathy (DR). Furthermore, we summarized the effects and mechanism of TCM on improving blood rheology, inhibiting aggregation of platelet, forming advanced glycation end products (AGEs), regulating oxidative stress, reducing blood fat, and improving lipid metabolism. The paper provides a new theoretical basis for the clinical practice of TCM in the prevention and treatment of DM and its microvascular complications. |
| format | Article |
| id | doaj-art-428a2942d32e429190e11f5503d2d6ad |
| institution | Kabale University |
| issn | 2314-6745 2314-6753 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Diabetes Research |
| spelling | doaj-art-428a2942d32e429190e11f5503d2d6ad2025-02-03T01:22:32ZengWileyJournal of Diabetes Research2314-67452314-67532016-01-01201610.1155/2016/10816571081657Administration of Traditional Chinese Blood Circulation Activating Drugs for Microvascular Complications in Patients with Type 2 Diabetes MellitusLisha He0Han Wang1Chengjuan Gu2Xinhui He3Linhua Zhao4Xiaolin Tong5Guang’anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, ChinaGuang’anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, ChinaGuang’anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, ChinaBeijing University of Chinese Medicine, Beijing 100029, ChinaGuang’anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, ChinaGuang’anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, ChinaTraditional Chinese medicine (TCM) is an important complementary strategy for treating diabetes mellitus (DM) in China. Traditional Chinese blood circulation activating drugs are intended to guide an overall approach to the prevention and treatment of microvascular complications of DM. The core mechanism is related to the protection of the vascular endothelium and the basement membrane. Here, we reviewed the scientific evidence underpinning the use of blood circulation activating drugs to prevent and treat DM-induced microvascular complications, including diabetic nephropathy (DN), diabetic peripheral neuropathy (DPN), and diabetic retinopathy (DR). Furthermore, we summarized the effects and mechanism of TCM on improving blood rheology, inhibiting aggregation of platelet, forming advanced glycation end products (AGEs), regulating oxidative stress, reducing blood fat, and improving lipid metabolism. The paper provides a new theoretical basis for the clinical practice of TCM in the prevention and treatment of DM and its microvascular complications.http://dx.doi.org/10.1155/2016/1081657 |
| spellingShingle | Lisha He Han Wang Chengjuan Gu Xinhui He Linhua Zhao Xiaolin Tong Administration of Traditional Chinese Blood Circulation Activating Drugs for Microvascular Complications in Patients with Type 2 Diabetes Mellitus Journal of Diabetes Research |
| title | Administration of Traditional Chinese Blood Circulation Activating Drugs for Microvascular Complications in Patients with Type 2 Diabetes Mellitus |
| title_full | Administration of Traditional Chinese Blood Circulation Activating Drugs for Microvascular Complications in Patients with Type 2 Diabetes Mellitus |
| title_fullStr | Administration of Traditional Chinese Blood Circulation Activating Drugs for Microvascular Complications in Patients with Type 2 Diabetes Mellitus |
| title_full_unstemmed | Administration of Traditional Chinese Blood Circulation Activating Drugs for Microvascular Complications in Patients with Type 2 Diabetes Mellitus |
| title_short | Administration of Traditional Chinese Blood Circulation Activating Drugs for Microvascular Complications in Patients with Type 2 Diabetes Mellitus |
| title_sort | administration of traditional chinese blood circulation activating drugs for microvascular complications in patients with type 2 diabetes mellitus |
| url | http://dx.doi.org/10.1155/2016/1081657 |
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