Anisotropic robust Poly(vinyl alcohol) hydrogels inspired by bio-tissue
Poly(vinyl alcohol) (PVA) hydrogels have enormous potential for tissue engineering and sensors owing to their biocompatibility, and tailorable mechanical properties. However, developing PVA hydrogels with high strength and toughness remains a significant challenge. In this work, inspired by bio-tiss...
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| Format: | Article |
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Elsevier
2025-02-01
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| Series: | Materials & Design |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S0264127525000334 |
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| author | Qifeng Jin Suli Xing Su Ju Ya Cao Ke Duan Li Jin Yulin Zhang Yonglyu He Jinyao Chen Jianwei Zhang |
| author_facet | Qifeng Jin Suli Xing Su Ju Ya Cao Ke Duan Li Jin Yulin Zhang Yonglyu He Jinyao Chen Jianwei Zhang |
| author_sort | Qifeng Jin |
| collection | DOAJ |
| description | Poly(vinyl alcohol) (PVA) hydrogels have enormous potential for tissue engineering and sensors owing to their biocompatibility, and tailorable mechanical properties. However, developing PVA hydrogels with high strength and toughness remains a significant challenge. In this work, inspired by bio-tissues that possess hierarchical anisotropic structures, a novel strong and tough PVA hydrogel was developed by using directional freeze-casting method and multiple physical bond-forming approach. The tensile strength and toughness of the resulted PVA hydrogel are 3.7 MPa and 3.27 MJ⋅m−3, which are 7.7 times and 9.9 times greater than those of conventional PVA hydrogels produced by freeze-casting method. The excellent mechanical properties of developed PVA hydrogels are attributed to two aspects: 1) the constructed anisotropic aligned pore wall structures played a key role in distributing the stress and thus impede local crack initiation and propagation, and 2) the formation of abundant sacrificial hydrogen bonds which effectively dissipate energy through dynamic breaking and reformation. The research provides a feasible approach to fabricating bioinspired PVA hydrogels with hierarchical architectures and excellent mechanical performances. |
| format | Article |
| id | doaj-art-427eec9b670f41c29279d8c3d33ed399 |
| institution | Kabale University |
| issn | 0264-1275 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Materials & Design |
| spelling | doaj-art-427eec9b670f41c29279d8c3d33ed3992025-01-23T05:26:17ZengElsevierMaterials & Design0264-12752025-02-01250113613Anisotropic robust Poly(vinyl alcohol) hydrogels inspired by bio-tissueQifeng Jin0Suli Xing1Su Ju2Ya Cao3Ke Duan4Li Jin5Yulin Zhang6Yonglyu He7Jinyao Chen8Jianwei Zhang9Department of Material Science and Engineering, College of Aerospace Science and Engineering, National University of Defense Technology, Changsha 410073, ChinaDepartment of Material Science and Engineering, College of Aerospace Science and Engineering, National University of Defense Technology, Changsha 410073, ChinaDepartment of Material Science and Engineering, College of Aerospace Science and Engineering, National University of Defense Technology, Changsha 410073, ChinaState Key Laboratory of Polymer Materials Engineering, Polymer Research Institute of Sichuan University, Chengdu 610065, ChinaDepartment of Material Science and Engineering, College of Aerospace Science and Engineering, National University of Defense Technology, Changsha 410073, ChinaDepartment of Material Science and Engineering, College of Aerospace Science and Engineering, National University of Defense Technology, Changsha 410073, ChinaDepartment of Material Science and Engineering, College of Aerospace Science and Engineering, National University of Defense Technology, Changsha 410073, ChinaDepartment of Material Science and Engineering, College of Aerospace Science and Engineering, National University of Defense Technology, Changsha 410073, ChinaState Key Laboratory of Polymer Materials Engineering, Polymer Research Institute of Sichuan University, Chengdu 610065, China; Corresponding authors.Department of Material Science and Engineering, College of Aerospace Science and Engineering, National University of Defense Technology, Changsha 410073, China; Corresponding authors.Poly(vinyl alcohol) (PVA) hydrogels have enormous potential for tissue engineering and sensors owing to their biocompatibility, and tailorable mechanical properties. However, developing PVA hydrogels with high strength and toughness remains a significant challenge. In this work, inspired by bio-tissues that possess hierarchical anisotropic structures, a novel strong and tough PVA hydrogel was developed by using directional freeze-casting method and multiple physical bond-forming approach. The tensile strength and toughness of the resulted PVA hydrogel are 3.7 MPa and 3.27 MJ⋅m−3, which are 7.7 times and 9.9 times greater than those of conventional PVA hydrogels produced by freeze-casting method. The excellent mechanical properties of developed PVA hydrogels are attributed to two aspects: 1) the constructed anisotropic aligned pore wall structures played a key role in distributing the stress and thus impede local crack initiation and propagation, and 2) the formation of abundant sacrificial hydrogen bonds which effectively dissipate energy through dynamic breaking and reformation. The research provides a feasible approach to fabricating bioinspired PVA hydrogels with hierarchical architectures and excellent mechanical performances.http://www.sciencedirect.com/science/article/pii/S0264127525000334PVA hydrogelsHierarchical anisotropic structureHydrogel bondsFreeze-casting method |
| spellingShingle | Qifeng Jin Suli Xing Su Ju Ya Cao Ke Duan Li Jin Yulin Zhang Yonglyu He Jinyao Chen Jianwei Zhang Anisotropic robust Poly(vinyl alcohol) hydrogels inspired by bio-tissue Materials & Design PVA hydrogels Hierarchical anisotropic structure Hydrogel bonds Freeze-casting method |
| title | Anisotropic robust Poly(vinyl alcohol) hydrogels inspired by bio-tissue |
| title_full | Anisotropic robust Poly(vinyl alcohol) hydrogels inspired by bio-tissue |
| title_fullStr | Anisotropic robust Poly(vinyl alcohol) hydrogels inspired by bio-tissue |
| title_full_unstemmed | Anisotropic robust Poly(vinyl alcohol) hydrogels inspired by bio-tissue |
| title_short | Anisotropic robust Poly(vinyl alcohol) hydrogels inspired by bio-tissue |
| title_sort | anisotropic robust poly vinyl alcohol hydrogels inspired by bio tissue |
| topic | PVA hydrogels Hierarchical anisotropic structure Hydrogel bonds Freeze-casting method |
| url | http://www.sciencedirect.com/science/article/pii/S0264127525000334 |
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