Telomerase and mitochondria inhibition promote apoptosis and TET2 and ANMT3a expression in triple negative breast cancer cell lines

Telomerase and mitochondria inhibition promote apoptosis and TET2 and ANMT3a expression in triple negative breast cancer cell lines

Introduction: High metastasis, resistance to common treatments, and high mortality rate, has made triple-negative breast cancer (TNBC) to be the most invasive type of breast cancer. High telomerase activity and mitochondrial biogenesis are involved in breast cancer tumorigenesis. The catalytic subun...

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Main Authors: Zeinab Mazloumi, Ali Rafat, Khadijeh Dizaji Asl, Mohammad Karimipour, Dariush Shanehbandi, Mehdi Talebi, Majid Montazer, Ali Akbar Movassaghpour, Alireza Dehnad, Raheleh Farahzadi, Hojjatollah Nozad Charoudeh
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2024-07-01
Series:BioImpacts
Subjects:
cancer stem cell
telomerase
mitochondria
apoptosis
dnmt3a
triple negative breast ‎cancer
Online Access:https://bi.tbzmed.ac.ir/PDF/bi-14-27640.pdf
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